Exploring the Potential of Biomimetic Peptides in Targeting Fibrillar and Filamentous Alpha-Synuclein—An In Silico and Experimental Approach to Parkinson’s Disease

Exploring the Potential of Biomimetic Peptides in Targeting Fibrillar and Filamentous Alpha-Synuclein—An In Silico and Experimental Approach to Parkinson’s Disease

Alpha-synuclein (ASyn) is a protein that is known to play a critical role in Parkinson’s disease (PD) due to its propensity for misfolding and aggregation. Furthermore, this process leads to oxidative stress and the formation of free radicals that cause neuronal damage. In this study, we have utiliz...

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Bibliographic Details
Main Authors: Sophia A. Frantzeskos, Mary A. Biggs, Ipsita A. Banerjee
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Biomimetics
Subjects:
alpha-synuclein
fibrillation
peptides
antioxidant
molecular dynamics
Online Access:https://www.mdpi.com/2313-7673/9/11/705
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