Efficient and accurate non-invasive tumor monitoring and diagnosis by interpretable deep learning

Efficient and accurate non-invasive tumor monitoring and diagnosis by interpretable deep learning

Summary: Detecting tumor-specific DNA methylation in circulating tumor DNA (ctDNA) offers a non-invasive method for tumor detection. The primary challenge lies in identifying the extremely low abundance of ctDNA in cell-free blood plasma (cfDNA). In this study, we present Oncoder, an interpretable d...

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Bibliographic Details
Main Authors: Youpeng Yang, Jiaying Liu, Yutong He, Yingjie Yang, Tao Jiang, Jia Tang, Xin Li
Format: Article
Language:English
Published: Elsevier 2025-08-01
Series:iScience
Subjects:
Cancer
Artificial intelligence
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004225014191
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