Intermittent Exposure to Hypobaric Hypoxia Increases VEGF, HIF-1α, and Nrf-2 Expressions in Brain Tissue

BACKGROUND: Hypoxia inducible factor-1α (HIF-1α), nuclear factor erythroid 2-related factor 2 (Nrf-2), and vascular endothelial growth factor (VEGF), play a crucial role as neuroprotective factors. Currently, there is a lack of studies examining the biomolecular responses of the brain to intermitten...

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Main Authors: Wardaya Wardaya, Dewi Sukmawati, Nurhadi Ibrahim, Frans Ferdinal, Ninik Mudjihartini, Mohamad Sadikin, Sri Widia A. Jusman, Irawan Satriotomo, Wawan Mulyawan
Format: Article
Language:English
Published: Secretariat of The Indonesian Biomedical Journal 2025-04-01
Series:Indonesian Biomedical Journal
Online Access:https://inabj.org/index.php/ibj/article/view/3519
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