Unveiling the potential of a whey protein- and leucine-enriched multi-nutrient formula high in vitamin D3: A scoping review on its role in enhancing body composition, strength, and physical function in sarcopenia
Objective: Nutritional intervention studies have indicated that whey protein- and leucine-enriched multi-nutrient formulas high in vitamin D3 are optimal medical nutrition recipes for treating sarcopenia. The present study undertakes a scoping review of research on whey protein- and leucine-enriched...
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Elsevier
2024-12-01
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| Series: | Archives of Gerontology and Geriatrics Plus |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2950307824000559 |
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| author | Daniel A. Traylor Everson A. Nunes Matthew Lees Mitchell J. Plucinski Megan Vondrasek Stuart M. Phillips |
| author_facet | Daniel A. Traylor Everson A. Nunes Matthew Lees Mitchell J. Plucinski Megan Vondrasek Stuart M. Phillips |
| author_sort | Daniel A. Traylor |
| collection | DOAJ |
| description | Objective: Nutritional intervention studies have indicated that whey protein- and leucine-enriched multi-nutrient formulas high in vitamin D3 are optimal medical nutrition recipes for treating sarcopenia. The present study undertakes a scoping review of research on whey protein- and leucine-enriched multi-nutrient formulas high in vitamin D3 in older adults with sarcopenia to highlight the impact of feeding and feeding with exercise on body composition, strength, and physical function. Design: Online databases identified studies published from 2005-2023, for which we selected 11 English-language studies that experimented with a whey protein—and leucine-enriched multi-nutrient formula(e) high in vitamin D3 on measures of sarcopenia as the primary outcome variables in older adults diagnosed as sarcopenic. Results: Nine registered human clinical trials and two unregistered human clinical trials were included in the analysis. All studies included sarcopenic older adults ages 66.5 y to 86.5 y. Two intervention types were identified: nutrition only or nutrition + exercise rehabilitation. The nutritional interventions improved lean mass, strength, and physical function. Conclusion: There is evidence for the effectiveness of several types of whey protein- and leucine-enriched multi-nutrient formulas high in vitamin D3 in improving lean mass and physical performance in older adults recovering from sarcopenia. This is the first scoping review to show that specific formula(e) used with rehabilitation programs can alleviate sarcopenic obesity, support skeletal bone, and improve body composition, lean mass, and physical function with or without exercise (CRD42022342953). |
| format | Article |
| id | doaj-art-51b7f5b08084403c9670379c4dc820f2 |
| institution | OA Journals |
| issn | 2950-3078 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Archives of Gerontology and Geriatrics Plus |
| spelling | doaj-art-51b7f5b08084403c9670379c4dc820f22025-08-20T01:55:32ZengElsevierArchives of Gerontology and Geriatrics Plus2950-30782024-12-011410005810.1016/j.aggp.2024.100058Unveiling the potential of a whey protein- and leucine-enriched multi-nutrient formula high in vitamin D3: A scoping review on its role in enhancing body composition, strength, and physical function in sarcopeniaDaniel A. Traylor0Everson A. Nunes1Matthew Lees2Mitchell J. Plucinski3Megan Vondrasek4Stuart M. Phillips5Department of Exercise Science and Athletic Training, Adrian College, Adrian, Michigan, United States; Corresponding author at: Department of Exercise Science and Athletic Training, Adrian College, 110 S Madison St. Adrian, Michigan 49221, United StatesDepartment of Kinesiology, McMaster University, Hamilton, Ontario, CanadaDepartment of Kinesiology, McMaster University, Hamilton, Ontario, CanadaDepartment of Exercise Science and Athletic Training, Adrian College, Adrian, Michigan, United StatesDepartment of Exercise Science and Athletic Training, Adrian College, Adrian, Michigan, United StatesDepartment of Kinesiology, McMaster University, Hamilton, Ontario, CanadaObjective: Nutritional intervention studies have indicated that whey protein- and leucine-enriched multi-nutrient formulas high in vitamin D3 are optimal medical nutrition recipes for treating sarcopenia. The present study undertakes a scoping review of research on whey protein- and leucine-enriched multi-nutrient formulas high in vitamin D3 in older adults with sarcopenia to highlight the impact of feeding and feeding with exercise on body composition, strength, and physical function. Design: Online databases identified studies published from 2005-2023, for which we selected 11 English-language studies that experimented with a whey protein—and leucine-enriched multi-nutrient formula(e) high in vitamin D3 on measures of sarcopenia as the primary outcome variables in older adults diagnosed as sarcopenic. Results: Nine registered human clinical trials and two unregistered human clinical trials were included in the analysis. All studies included sarcopenic older adults ages 66.5 y to 86.5 y. Two intervention types were identified: nutrition only or nutrition + exercise rehabilitation. The nutritional interventions improved lean mass, strength, and physical function. Conclusion: There is evidence for the effectiveness of several types of whey protein- and leucine-enriched multi-nutrient formulas high in vitamin D3 in improving lean mass and physical performance in older adults recovering from sarcopenia. This is the first scoping review to show that specific formula(e) used with rehabilitation programs can alleviate sarcopenic obesity, support skeletal bone, and improve body composition, lean mass, and physical function with or without exercise (CRD42022342953).http://www.sciencedirect.com/science/article/pii/S2950307824000559 |
| spellingShingle | Daniel A. Traylor Everson A. Nunes Matthew Lees Mitchell J. Plucinski Megan Vondrasek Stuart M. Phillips Unveiling the potential of a whey protein- and leucine-enriched multi-nutrient formula high in vitamin D3: A scoping review on its role in enhancing body composition, strength, and physical function in sarcopenia Archives of Gerontology and Geriatrics Plus |
| title | Unveiling the potential of a whey protein- and leucine-enriched multi-nutrient formula high in vitamin D3: A scoping review on its role in enhancing body composition, strength, and physical function in sarcopenia |
| title_full | Unveiling the potential of a whey protein- and leucine-enriched multi-nutrient formula high in vitamin D3: A scoping review on its role in enhancing body composition, strength, and physical function in sarcopenia |
| title_fullStr | Unveiling the potential of a whey protein- and leucine-enriched multi-nutrient formula high in vitamin D3: A scoping review on its role in enhancing body composition, strength, and physical function in sarcopenia |
| title_full_unstemmed | Unveiling the potential of a whey protein- and leucine-enriched multi-nutrient formula high in vitamin D3: A scoping review on its role in enhancing body composition, strength, and physical function in sarcopenia |
| title_short | Unveiling the potential of a whey protein- and leucine-enriched multi-nutrient formula high in vitamin D3: A scoping review on its role in enhancing body composition, strength, and physical function in sarcopenia |
| title_sort | unveiling the potential of a whey protein and leucine enriched multi nutrient formula high in vitamin d3 a scoping review on its role in enhancing body composition strength and physical function in sarcopenia |
| url | http://www.sciencedirect.com/science/article/pii/S2950307824000559 |
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