Postishemic Cerebral Function and Blood Flow
The impact of massive blood loss on cerebral blood flow-function relationships was studied in rats in the postis-chemic period. Anxiety was examined in the raised cross-shaped labyrinth. Cerebral blood flow was registered by a laser Doppler flowmeter. One-hour massive blood flow substantially increa...
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| Format: | Article |
| Language: | English |
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Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, Russia
2005-08-01
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| Series: | Общая реаниматология |
| Online Access: | https://www.reanimatology.com/rmt/article/view/1243 |
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| author | V. V. Aleksandrin V. L. Kozhura I. S. Novoderzhkina Ye. Yu. Parshina |
| author_facet | V. V. Aleksandrin V. L. Kozhura I. S. Novoderzhkina Ye. Yu. Parshina |
| author_sort | V. V. Aleksandrin |
| collection | DOAJ |
| description | The impact of massive blood loss on cerebral blood flow-function relationships was studied in rats in the postis-chemic period. Anxiety was examined in the raised cross-shaped labyrinth. Cerebral blood flow was registered by a laser Doppler flowmeter. One-hour massive blood flow substantially increased the level of anxiety in 75% of the rats following 7 and 20 days. There were no significant behavior changes in 25% of the animals. Experimental animals with preserved behavioral parameters showed cerebral blood flow resistance to ischemia and reperfusion while rats with increased anxiety were found to have delayed postischemic hypoperfusion. Thus, a relationship was found between the behavior of the rats and the resistance of cerebral blood flow to ischemia and reperfusion. |
| format | Article |
| id | doaj-art-51b2b88f0ec54cc9a78709bdec45ba81 |
| institution | DOAJ |
| issn | 1813-9779 2411-7110 |
| language | English |
| publishDate | 2005-08-01 |
| publisher | Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, Russia |
| record_format | Article |
| series | Общая реаниматология |
| spelling | doaj-art-51b2b88f0ec54cc9a78709bdec45ba812025-08-20T03:18:50ZengFederal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, RussiaОбщая реаниматология1813-97792411-71102005-08-0114232610.15360/1813-9779-2005-4-23-261243Postishemic Cerebral Function and Blood FlowV. V. Aleksandrin0V. L. Kozhura1I. S. Novoderzhkina2Ye. Yu. Parshina3Laboratory of Experimental Therapy for Terminal States, Research Institute of General Reanimatology, Russian Academy of Medical Sciences, MoscowLaboratory of Experimental Therapy for Terminal States, Research Institute of General Reanimatology, Russian Academy of Medical Sciences, MoscowLaboratory of Experimental Therapy for Terminal States, Research Institute of General Reanimatology, Russian Academy of Medical Sciences, MoscowLaboratory of Experimental Therapy for Terminal States, Research Institute of General Reanimatology, Russian Academy of Medical Sciences, MoscowThe impact of massive blood loss on cerebral blood flow-function relationships was studied in rats in the postis-chemic period. Anxiety was examined in the raised cross-shaped labyrinth. Cerebral blood flow was registered by a laser Doppler flowmeter. One-hour massive blood flow substantially increased the level of anxiety in 75% of the rats following 7 and 20 days. There were no significant behavior changes in 25% of the animals. Experimental animals with preserved behavioral parameters showed cerebral blood flow resistance to ischemia and reperfusion while rats with increased anxiety were found to have delayed postischemic hypoperfusion. Thus, a relationship was found between the behavior of the rats and the resistance of cerebral blood flow to ischemia and reperfusion.https://www.reanimatology.com/rmt/article/view/1243 |
| spellingShingle | V. V. Aleksandrin V. L. Kozhura I. S. Novoderzhkina Ye. Yu. Parshina Postishemic Cerebral Function and Blood Flow Общая реаниматология |
| title | Postishemic Cerebral Function and Blood Flow |
| title_full | Postishemic Cerebral Function and Blood Flow |
| title_fullStr | Postishemic Cerebral Function and Blood Flow |
| title_full_unstemmed | Postishemic Cerebral Function and Blood Flow |
| title_short | Postishemic Cerebral Function and Blood Flow |
| title_sort | postishemic cerebral function and blood flow |
| url | https://www.reanimatology.com/rmt/article/view/1243 |
| work_keys_str_mv | AT vvaleksandrin postishemiccerebralfunctionandbloodflow AT vlkozhura postishemiccerebralfunctionandbloodflow AT isnovoderzhkina postishemiccerebralfunctionandbloodflow AT yeyuparshina postishemiccerebralfunctionandbloodflow |