Recent Advances in the Surgical Treatment of Differentiated Thyroid Cancer: A Comprehensive Review

Differentiated thyroid cancers have become one of the fastest growing malignancies in the world. While surgery has remained the cornerstone of management of these tumors, the surgical approach has seen numerous innovations over the past few decades. The use of video-assistance and robotics has revol...

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Main Authors: Raghunandan Venkat, Marlon A. Guerrero
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:The Scientific World Journal
Online Access:http://dx.doi.org/10.1155/2013/425136
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author Raghunandan Venkat
Marlon A. Guerrero
author_facet Raghunandan Venkat
Marlon A. Guerrero
author_sort Raghunandan Venkat
collection DOAJ
description Differentiated thyroid cancers have become one of the fastest growing malignancies in the world. While surgery has remained the cornerstone of management of these tumors, the surgical approach has seen numerous innovations over the past few decades. The use of video-assistance and robotics has revolutionized thyroid surgery. This paper provides a comprehensive evaluation of the different approaches to thyroid surgery, the utility of prophylactic and therapeutic lymph node dissection, and evidence-based guidelines in the treatment of differentiated thyroid cancers. Minimally invasive video-ssisted thyroidectomy is both safe and effective in the hands of the trained surgeon and, in selected patient populations, has comparative perioperative morbidity and better cosmesis as compared to conventional open thyroidectomy. It is universally accepted that therapeutic central lymph node dissection should be performed when metastatic lymph nodes are identified on physical exam, ultrasound, or intraoperatively. In the absence of overt nodal metastasis, the role of elective prophylactic central lymph node dissection remains a matter of debate and prospective, randomized studies are warranted to evaluate the utility of this procedure.
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spelling doaj-art-51a7e97b522e4bf6913c3587e23964132025-02-03T06:13:57ZengWileyThe Scientific World Journal1537-744X2013-01-01201310.1155/2013/425136425136Recent Advances in the Surgical Treatment of Differentiated Thyroid Cancer: A Comprehensive ReviewRaghunandan Venkat0Marlon A. Guerrero1Division of Surgical Oncology, Department of Surgery, University of Arizona, P.O. Box 245131, Tucson, AZ 85724-5131, USADivision of Surgical Oncology, Department of Surgery, University of Arizona, P.O. Box 245131, Tucson, AZ 85724-5131, USADifferentiated thyroid cancers have become one of the fastest growing malignancies in the world. While surgery has remained the cornerstone of management of these tumors, the surgical approach has seen numerous innovations over the past few decades. The use of video-assistance and robotics has revolutionized thyroid surgery. This paper provides a comprehensive evaluation of the different approaches to thyroid surgery, the utility of prophylactic and therapeutic lymph node dissection, and evidence-based guidelines in the treatment of differentiated thyroid cancers. Minimally invasive video-ssisted thyroidectomy is both safe and effective in the hands of the trained surgeon and, in selected patient populations, has comparative perioperative morbidity and better cosmesis as compared to conventional open thyroidectomy. It is universally accepted that therapeutic central lymph node dissection should be performed when metastatic lymph nodes are identified on physical exam, ultrasound, or intraoperatively. In the absence of overt nodal metastasis, the role of elective prophylactic central lymph node dissection remains a matter of debate and prospective, randomized studies are warranted to evaluate the utility of this procedure.http://dx.doi.org/10.1155/2013/425136
spellingShingle Raghunandan Venkat
Marlon A. Guerrero
Recent Advances in the Surgical Treatment of Differentiated Thyroid Cancer: A Comprehensive Review
The Scientific World Journal
title Recent Advances in the Surgical Treatment of Differentiated Thyroid Cancer: A Comprehensive Review
title_full Recent Advances in the Surgical Treatment of Differentiated Thyroid Cancer: A Comprehensive Review
title_fullStr Recent Advances in the Surgical Treatment of Differentiated Thyroid Cancer: A Comprehensive Review
title_full_unstemmed Recent Advances in the Surgical Treatment of Differentiated Thyroid Cancer: A Comprehensive Review
title_short Recent Advances in the Surgical Treatment of Differentiated Thyroid Cancer: A Comprehensive Review
title_sort recent advances in the surgical treatment of differentiated thyroid cancer a comprehensive review
url http://dx.doi.org/10.1155/2013/425136
work_keys_str_mv AT raghunandanvenkat recentadvancesinthesurgicaltreatmentofdifferentiatedthyroidcanceracomprehensivereview
AT marlonaguerrero recentadvancesinthesurgicaltreatmentofdifferentiatedthyroidcanceracomprehensivereview