Herbal formula (Danggui Beimu Kushen Wan) for prostate disorders: a systematic review of classical literature

Background: Danggui Beimu Kushen Wan (DBKW) was initially known for difficult urination in pregnancy and has been widely used for prostate disorders in modern days. This study aimed to comprehensively investigate the implications of DBKW in traditional evidence. Methods: The Encyclopedia of Traditio...

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Main Authors: Hong Li, Andrew Hung, Angela Wei Hong Yang
Format: Article
Language:English
Published: Elsevier 2019-12-01
Series:Integrative Medicine Research
Online Access:http://www.sciencedirect.com/science/article/pii/S2213422019301672
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author Hong Li
Andrew Hung
Angela Wei Hong Yang
author_facet Hong Li
Andrew Hung
Angela Wei Hong Yang
author_sort Hong Li
collection DOAJ
description Background: Danggui Beimu Kushen Wan (DBKW) was initially known for difficult urination in pregnancy and has been widely used for prostate disorders in modern days. This study aimed to comprehensively investigate the implications of DBKW in traditional evidence. Methods: The Encyclopedia of Traditional Chinese Medicine was searched to identify the ingredients, dosage, etiologies, pathogeneses, actions and indications related to DBKW documented in ancient books. Descriptive summary was provided to their characteristics. Results: A total of 41 texts in 36 classic books were included. Two etiologies and 10 pathogeneses were investigated. All the identified formulas contain Angelicae Sinensis Radix, Fritillariae Thunbergii Bulbus and Sophorae Flavescentis Radix with the ratio of 1:1:1. The treatment dosage is three to 10 pills each time. The primary indication of DBKW is difficult urination with heat stagnation. Nine included texts specified that this formula could also be used for male. Conclusion: Included classic literature has provided fundamental evidence for the management of difficult urination in female and male. Further studies should investigate its mechanisms of actions for difficult urination related conditions, such as prostate disorders. Keywords: Herbal medicine, Prostate disorder, Urination, Classic literature, Text mining.
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spelling doaj-art-519e734e97964222bdbe0cb5e2c0a0162025-08-20T03:52:07ZengElsevierIntegrative Medicine Research2213-42202019-12-018424024610.1016/j.imr.2019.08.006Herbal formula (Danggui Beimu Kushen Wan) for prostate disorders: a systematic review of classical literatureHong Li0Andrew Hung1Angela Wei Hong Yang2School of Health and Biomedical Sciences, RMIT University, Bundoora, AustraliaSchool of Science, RMIT University, Bundoora, AustraliaSchool of Health and Biomedical Sciences, RMIT University, Bundoora, Australia; Corresponding author at: Discipline of Chinese Medicine, School of Health and Biomedical Sciences, RMIT University, PO Box 71, Bundoora, Victoria 3083, Australia.Background: Danggui Beimu Kushen Wan (DBKW) was initially known for difficult urination in pregnancy and has been widely used for prostate disorders in modern days. This study aimed to comprehensively investigate the implications of DBKW in traditional evidence. Methods: The Encyclopedia of Traditional Chinese Medicine was searched to identify the ingredients, dosage, etiologies, pathogeneses, actions and indications related to DBKW documented in ancient books. Descriptive summary was provided to their characteristics. Results: A total of 41 texts in 36 classic books were included. Two etiologies and 10 pathogeneses were investigated. All the identified formulas contain Angelicae Sinensis Radix, Fritillariae Thunbergii Bulbus and Sophorae Flavescentis Radix with the ratio of 1:1:1. The treatment dosage is three to 10 pills each time. The primary indication of DBKW is difficult urination with heat stagnation. Nine included texts specified that this formula could also be used for male. Conclusion: Included classic literature has provided fundamental evidence for the management of difficult urination in female and male. Further studies should investigate its mechanisms of actions for difficult urination related conditions, such as prostate disorders. Keywords: Herbal medicine, Prostate disorder, Urination, Classic literature, Text mining.http://www.sciencedirect.com/science/article/pii/S2213422019301672
spellingShingle Hong Li
Andrew Hung
Angela Wei Hong Yang
Herbal formula (Danggui Beimu Kushen Wan) for prostate disorders: a systematic review of classical literature
Integrative Medicine Research
title Herbal formula (Danggui Beimu Kushen Wan) for prostate disorders: a systematic review of classical literature
title_full Herbal formula (Danggui Beimu Kushen Wan) for prostate disorders: a systematic review of classical literature
title_fullStr Herbal formula (Danggui Beimu Kushen Wan) for prostate disorders: a systematic review of classical literature
title_full_unstemmed Herbal formula (Danggui Beimu Kushen Wan) for prostate disorders: a systematic review of classical literature
title_short Herbal formula (Danggui Beimu Kushen Wan) for prostate disorders: a systematic review of classical literature
title_sort herbal formula danggui beimu kushen wan for prostate disorders a systematic review of classical literature
url http://www.sciencedirect.com/science/article/pii/S2213422019301672
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