Derivation and validation of an algorithm to predict transitions from community to residential long-term care among persons with dementia-A retrospective cohort study.

Derivation and validation of an algorithm to predict transitions from community to residential long-term care among persons with dementia-A retrospective cohort study.

<h4>Objectives</h4>To develop and validate a model to predict time-to-LTC admissions among individuals with dementia.<h4>Design</h4>Population-based retrospective cohort study using health administrative data.<h4>Setting and participants</h4>Community-dwelling old...

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Bibliographic Details
Main Authors: Wenshan Li, Luke Turcotte, Amy T Hsu, Robert Talarico, Danial Qureshi, Colleen Webber, Steven Hawken, Peter Tanuseputro, Douglas G Manuel, Greg Huyer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-10-01
Series:PLOS Digital Health
Online Access:https://doi.org/10.1371/journal.pdig.0000441
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Summary:<h4>Objectives</h4>To develop and validate a model to predict time-to-LTC admissions among individuals with dementia.<h4>Design</h4>Population-based retrospective cohort study using health administrative data.<h4>Setting and participants</h4>Community-dwelling older adults (65+) in Ontario living with dementia and assessed with the Resident Assessment Instrument for Home Care (RAI-HC) between April 1, 2010 and March 31, 2017.<h4>Methods</h4>Individuals in the derivation cohort (n = 95,813; assessed before March 31, 2015) were followed for up to 360 days after the index RAI-HC assessment for admission into LTC. We used a multivariable Fine Gray sub-distribution hazard model to predict the cumulative incidence of LTC entry while accounting for all-cause mortality as a competing risk. The model was validated in 34,038 older adults with dementia with an index RAI-HC assessment between April 1, 2015 and March 31, 2017.<h4>Results</h4>Within one year of a RAI-HC assessment, 35,513 (37.1%) individuals in the derivation cohort and 10,735 (31.5%) in the validation cohort entered LTC. Our algorithm was well-calibrated (Emax = 0.119, ICIavg = 0.057) and achieved a c-statistic of 0.707 (95% confidence interval: 0.703-0.712) in the validation cohort.<h4>Conclusions and implications</h4>We developed an algorithm to predict time to LTC entry among individuals living with dementia. This tool can inform care planning for individuals with dementia and their family caregivers.
ISSN:2767-3170

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