Large-sized polystyrene microplastics induce oxidative stress in AML12 cells

Large-sized polystyrene microplastics induce oxidative stress in AML12 cells

Abstract Microplastics (MPs), particularly those exceeding 20 μm in diameter, are increasingly detected in environment and animal tissues, yet their cytotoxicity remains poorly understood. While existing studies focused on MPs with relatively small sizes (≤ 20 μm) or nanoplastics (NPs), the biologic...

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Bibliographic Details
Main Authors: Bitian Zhao, Rui Liu, Shuhao Guo, Shiyu Li, Zekai Huang, Yihan Wang, Cuiping Yu, Zhijun Hou, Yuanyuan Zhang, Yanlong Zhang, Xuedong Liu
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Large-sized microplastics
Polystyrene
Oxidative stress
Apoptosis
Ferroptosis
Online Access:https://doi.org/10.1038/s41598-025-11577-8
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