Imaging approaches in risk stratification of patients with coronary artery disease: a narrative review
Coronary artery disease (CAD) is the most common cause of mortality among adults worldwide. In the prognostic risk stratification of these patients, crucial determinants are lumen stenosis, total volume and composition of the plaque. Considering that most of the myocardial infarctions are due to non...
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| Format: | Article |
| Language: | English |
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Termedia Publishing House
2024-06-01
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| Series: | Archives of Medical Science |
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| Online Access: | https://www.archivesofmedicalscience.com/Imaging-approaches-in-risk-stratification-of-patients-with-coronary-artery-disease,188808,0,2.html |
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| _version_ | 1850135001014730752 |
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| author | Gloria Santangelo Elisa Gherbesi Luca Donisi Andrea Faggiano Luca Bergamaschi Carmine Pizzi Stefano Carugo Massimiliano Ruscica Pompilio Faggiano |
| author_facet | Gloria Santangelo Elisa Gherbesi Luca Donisi Andrea Faggiano Luca Bergamaschi Carmine Pizzi Stefano Carugo Massimiliano Ruscica Pompilio Faggiano |
| author_sort | Gloria Santangelo |
| collection | DOAJ |
| description | Coronary artery disease (CAD) is the most common cause of mortality among adults worldwide. In the prognostic risk stratification of these patients, crucial determinants are lumen stenosis, total volume and composition of the plaque. Considering that most of the myocardial infarctions are due to non-obstructive plaques or are associated with high-risk features, plaque composition can serve as an independent predictor of cardiac outcomes. Conversely, although there is a close relationship between ischemia and CAD severity, the assessment of the degree of ischemia, as a surrogate marker of the coronary plaque burden, remains a controversial issue. Thus, aim of this narrative review is to discuss the usefulness of the imaging methodologies to differentiate the ischemia vs the plaque burden in clinical practice. New diagnostic tools to evaluate the extent of the atheromatous coronary artery could help in tailoring a personalized therapeutic approach. |
| format | Article |
| id | doaj-art-518e968787b444069bae7cfda8ca6c3e |
| institution | OA Journals |
| issn | 1734-1922 1896-9151 |
| language | English |
| publishDate | 2024-06-01 |
| publisher | Termedia Publishing House |
| record_format | Article |
| series | Archives of Medical Science |
| spelling | doaj-art-518e968787b444069bae7cfda8ca6c3e2025-08-20T02:31:34ZengTermedia Publishing HouseArchives of Medical Science1734-19221896-91512024-06-01211163110.5114/aoms/188808188808Imaging approaches in risk stratification of patients with coronary artery disease: a narrative reviewGloria Santangelo0Elisa Gherbesi1Luca Donisi2Andrea Faggiano3Luca Bergamaschi4Carmine Pizzi5Stefano Carugo6Massimiliano Ruscica7https://orcid.org/0000-0002-0195-7061Pompilio Faggiano8Department of Cardio-Thoracic-Vascular Diseases, IRCCS Foundation Ca’ Granda Hospital Maggiore Polyclinic, Milan, ItalyDepartment of Cardio-Thoracic-Vascular Diseases, IRCCS Foundation Ca’ Granda Hospital Maggiore Polyclinic, Milan, ItalyDepartment of Cardio-Thoracic-Vascular Diseases, IRCCS Foundation Ca’ Granda Hospital Maggiore Polyclinic, Milan, ItalyDepartment of Cardio-Thoracic-Vascular Diseases, IRCCS Foundation Ca’ Granda Hospital Maggiore Polyclinic, Milan, ItalyCardiology Unit, IRCCS University Hospital of Bologna, Bologna, ItalyCardiology Unit, IRCCS University Hospital of Bologna, Bologna, ItalyDepartment of Cardio-Thoracic-Vascular Diseases, IRCCS Foundation Ca’ Granda Hospital Maggiore Polyclinic, Milan, ItalyDepartment of Clinical Sciences and Community Health, University of Milan, Milan, ItalyPoliambulance Foundation, Department of Cardiothoracic, Brescia, ItalyCoronary artery disease (CAD) is the most common cause of mortality among adults worldwide. In the prognostic risk stratification of these patients, crucial determinants are lumen stenosis, total volume and composition of the plaque. Considering that most of the myocardial infarctions are due to non-obstructive plaques or are associated with high-risk features, plaque composition can serve as an independent predictor of cardiac outcomes. Conversely, although there is a close relationship between ischemia and CAD severity, the assessment of the degree of ischemia, as a surrogate marker of the coronary plaque burden, remains a controversial issue. Thus, aim of this narrative review is to discuss the usefulness of the imaging methodologies to differentiate the ischemia vs the plaque burden in clinical practice. New diagnostic tools to evaluate the extent of the atheromatous coronary artery could help in tailoring a personalized therapeutic approach.https://www.archivesofmedicalscience.com/Imaging-approaches-in-risk-stratification-of-patients-with-coronary-artery-disease,188808,0,2.htmlcoronary artery diseaseatherosclerotic burdenplaquemyocardialischemiamultimodality imaging |
| spellingShingle | Gloria Santangelo Elisa Gherbesi Luca Donisi Andrea Faggiano Luca Bergamaschi Carmine Pizzi Stefano Carugo Massimiliano Ruscica Pompilio Faggiano Imaging approaches in risk stratification of patients with coronary artery disease: a narrative review Archives of Medical Science coronary artery disease atherosclerotic burden plaque myocardial ischemia multimodality imaging |
| title | Imaging approaches in risk stratification of patients with coronary artery disease: a narrative review |
| title_full | Imaging approaches in risk stratification of patients with coronary artery disease: a narrative review |
| title_fullStr | Imaging approaches in risk stratification of patients with coronary artery disease: a narrative review |
| title_full_unstemmed | Imaging approaches in risk stratification of patients with coronary artery disease: a narrative review |
| title_short | Imaging approaches in risk stratification of patients with coronary artery disease: a narrative review |
| title_sort | imaging approaches in risk stratification of patients with coronary artery disease a narrative review |
| topic | coronary artery disease atherosclerotic burden plaque myocardial ischemia multimodality imaging |
| url | https://www.archivesofmedicalscience.com/Imaging-approaches-in-risk-stratification-of-patients-with-coronary-artery-disease,188808,0,2.html |
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