Current approaches for Usher syndrome disease models and developing therapies

Current approaches for Usher syndrome disease models and developing therapies

Usher syndrome is a severely debilitating autosomal recessive disorder characterised by congenital or progressive hearing loss, gradual vision loss and in some subtypes, vestibular dysfunction. Much progress has been made in recent years in creating appropriate preclinical models for most subtypes o...

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Bibliographic Details
Main Authors: Fiona K. Leith, Joey Lye, Derek S. Delaney, Samuel McLenachan, Fred K. Chen, Marcus D. Atlas, Elaine Y. M. Wong
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Usher syndrome
hearing loss
inner ear
hair cell
gene therapy
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2025.1547523/full
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