Partial rejuvenation of the spermatogonial stem cell niche after gender-affirming hormone therapy in trans women

Partial rejuvenation of the spermatogonial stem cell niche after gender-affirming hormone therapy in trans women

Although the impact of gender-affirming hormone therapy (GAHT) on spermatogenesis in trans women has already been studied, data on its precise effects on the testicular environment is poor. Therefore, this study aimed to characterize, through histological and transcriptomic analysis, the spermatogon...

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Bibliographic Details
Main Authors: Emily Delgouffe, Samuel Madureira Silva, Frédéric Chalmel, Wilfried Cools, Camille Raets, Kelly Tilleman, Guy T'Sjoen, Yoni Baert, Ellen Goossens
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2025-01-01
Series:eLife
Subjects:
transgender women
spermatogonial stem cells
testicular tissue
spermatogenesis
hormonal treatment
germ cells
Online Access:https://elifesciences.org/articles/94825
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