Androgen receptor dynamics in prostate cancer: from disease progression to treatment resistance

Androgen receptor dynamics in prostate cancer: from disease progression to treatment resistance

Prostate cancer is the most common cancer among men worldwide, especially in those over 65, and is a leading cause of cancer-related mortality. The disease typically advances from an androgen-dependent state to castration-resistant prostate cancer (CRPC), which poses significant treatment challenges...

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Bibliographic Details
Main Authors: Caihong Li, Dongkai Cheng, Peng Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-02-01
Series:Frontiers in Oncology
Subjects:
prostate cancer
androgen receptor (AR)
epigenetics
drug resistance
personalized therapy
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2025.1542811/full
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