Phthalylglycyl chloride as a derivatization reagent for determination of urinary amino acids using ultra high-performance liquid chromatography coupled with high resolution mass spectrometry

Phthalylglycyl chloride as a derivatization reagent for determination of urinary amino acids using ultra high-performance liquid chromatography coupled with high resolution mass spectrometry

A new derivatization reagent, phthalylglycyl chloride (PG-Cl), for the analysis of urinary amino acids was demonstrated using reversed-phase ultra-high performance liquid chromatography coupled to electrospray ionization-quadrupole-time-of-flight mass spectrometer. The study compares the limits of d...

Full description

Saved in:
Bibliographic Details
Main Authors: Azamat Temerdashev, Pavel N. Nesterenko, Sanka N. Atapattu, Yu-Qi Feng, Maria Zorina, Kseniya Zhurkina, Elina Gashimova, Maxim O. Steshin, Victor V. Dotsenko
Format: Article
Language:English
Published: Elsevier 2024-11-01
Series:Journal of Chromatography Open
Subjects:
Derivatization
Sample preparation
Phthalylglycyl chloride
Non-targeted screening
UHPLC-MS/MS
HRMS
Online Access:http://www.sciencedirect.com/science/article/pii/S2772391724000495
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items