Efficacy and safety of PCSK-9 inhibitors in patients with acute coronary syndrome: a systematic review and network meta-analysis

Efficacy and safety of PCSK-9 inhibitors in patients with acute coronary syndrome: a systematic review and network meta-analysis

Abstract Background Acute coronary syndrome (ACS) remains a leading cause of global cardiovascular morbidity and mortality, with elevated low-density lipoprotein cholesterol (LDL-C) being a key modifiable risk factor. Despite statin therapy, many patients fail to achieve optimal LDL-C targets, highl...

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Bibliographic Details
Main Authors: Guoying Kao, Chuan Chen, Ying Zhang, Yi Xu, Gang Xu
Format: Article
Language:English
Published: BMC 2025-08-01
Series:BMC Cardiovascular Disorders
Subjects:
Acute coronary syndrome
PCSK-9
LDL-C
MACE
Network meta-analysis
Online Access:https://doi.org/10.1186/s12872-025-05070-3
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