Tai Chi improves balance, mobility and gait function of the lower limbs in patients with Parkinson's disease: a systematic review and meta-analysis

Abstract Objective This study aimed to systematically evaluate the effect of Tai Chi on the balance function, mobility function, and gait function (including gait endurance, gait amplitude, and gait speed) of the lower limbs in patients with Parkinson's disease. Methods The “PICOS” principle wa...

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Main Authors: Lijie Lou, Chunyu Xiang, Yingliang Hu, Jiapeng Yang
Format: Article
Language:English
Published: BMC 2025-02-01
Series:European Journal of Medical Research
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Online Access:https://doi.org/10.1186/s40001-024-02151-5
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author Lijie Lou
Chunyu Xiang
Yingliang Hu
Jiapeng Yang
author_facet Lijie Lou
Chunyu Xiang
Yingliang Hu
Jiapeng Yang
author_sort Lijie Lou
collection DOAJ
description Abstract Objective This study aimed to systematically evaluate the effect of Tai Chi on the balance function, mobility function, and gait function (including gait endurance, gait amplitude, and gait speed) of the lower limbs in patients with Parkinson's disease. Methods The “PICOS” principle was used to search seven English and six Chinese databases. Search for relevant studies published up to September 11, 2023, from the date of database creation. Two authors independently screened all eligible studies. The included studies were assessed for risk of bias based on the criteria outlined in Cochrane Handbook 5.1.0. Quantitative statistics and meta-analyses were conducted using Review Manager 5.4 software. Results Th 18 studies that met the inclusion criteria, 16 of which were included in the meta-analysis, included a sample of 963 cases from four countries. The meta-analysis revealed that Tai Chi was effective compared with conventional medication in improving balance function (MD = 2.06, 95% CI [1.35, 2.78], P < 0.00001, I2 =0%), mobility function (MD = − 1.59, 95% CI [− 2.28, − 0.91], P < 0.00001, I2 =14%), and gait speed (SMD =0.59, 95% [0.28, 0.91], P = 0.0002, I2 =29%). However, there was no significant improvement in gait endurance (SMD = 0.14, 95% CI [−0.41, 0.68], P =0.62, I2 = 0%) or gait amplitude (SMD =0.30 , 95% CI [− 0.00, 0.61], P = 0.05, I2 =0%). Compared with other exercise therapies, Tai Chi was significantly superior in improving balance function (MD = 3.05, 95% CI [1.94, 4.16], P <0.00001, I2 = 38%), mobility function (MD =−0.70, 95%CI [− 1.23, − 0.17], P = 0.01, I2 = 0%), and gait range (SMD = 0.36, 95% CI [0.14, 0.58], P = 0.002, I2 = 45%). However, the advantage of improving gait speed (SMD =0.00, 95% CI [− 0.28, 0.29], P = 0.98, I2 =0%) was uncertain. Conclusion Tai chi is a safe and effective rehabilitation intervention that can enhance the balance and mobility functions of the lower limbs in patients with Parkinson's disease.
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spelling doaj-art-517075e425c14da3bcf34bc6af86d42c2025-08-20T02:15:15ZengBMCEuropean Journal of Medical Research2047-783X2025-02-0130111310.1186/s40001-024-02151-5Tai Chi improves balance, mobility and gait function of the lower limbs in patients with Parkinson's disease: a systematic review and meta-analysisLijie Lou0Chunyu Xiang1Yingliang Hu2Jiapeng Yang3Graduate School, Guangzhou Sport UniversitySchool of Sports and Health, Guangdong Institute of Science and TechnologyGraduate School, Guangzhou Sport UniversityGraduate School, Guangzhou Sport UniversityAbstract Objective This study aimed to systematically evaluate the effect of Tai Chi on the balance function, mobility function, and gait function (including gait endurance, gait amplitude, and gait speed) of the lower limbs in patients with Parkinson's disease. Methods The “PICOS” principle was used to search seven English and six Chinese databases. Search for relevant studies published up to September 11, 2023, from the date of database creation. Two authors independently screened all eligible studies. The included studies were assessed for risk of bias based on the criteria outlined in Cochrane Handbook 5.1.0. Quantitative statistics and meta-analyses were conducted using Review Manager 5.4 software. Results Th 18 studies that met the inclusion criteria, 16 of which were included in the meta-analysis, included a sample of 963 cases from four countries. The meta-analysis revealed that Tai Chi was effective compared with conventional medication in improving balance function (MD = 2.06, 95% CI [1.35, 2.78], P < 0.00001, I2 =0%), mobility function (MD = − 1.59, 95% CI [− 2.28, − 0.91], P < 0.00001, I2 =14%), and gait speed (SMD =0.59, 95% [0.28, 0.91], P = 0.0002, I2 =29%). However, there was no significant improvement in gait endurance (SMD = 0.14, 95% CI [−0.41, 0.68], P =0.62, I2 = 0%) or gait amplitude (SMD =0.30 , 95% CI [− 0.00, 0.61], P = 0.05, I2 =0%). Compared with other exercise therapies, Tai Chi was significantly superior in improving balance function (MD = 3.05, 95% CI [1.94, 4.16], P <0.00001, I2 = 38%), mobility function (MD =−0.70, 95%CI [− 1.23, − 0.17], P = 0.01, I2 = 0%), and gait range (SMD = 0.36, 95% CI [0.14, 0.58], P = 0.002, I2 = 45%). However, the advantage of improving gait speed (SMD =0.00, 95% CI [− 0.28, 0.29], P = 0.98, I2 =0%) was uncertain. Conclusion Tai chi is a safe and effective rehabilitation intervention that can enhance the balance and mobility functions of the lower limbs in patients with Parkinson's disease.https://doi.org/10.1186/s40001-024-02151-5Tai ChiParkinson's diseaseLower limbsMeta-analysis
spellingShingle Lijie Lou
Chunyu Xiang
Yingliang Hu
Jiapeng Yang
Tai Chi improves balance, mobility and gait function of the lower limbs in patients with Parkinson's disease: a systematic review and meta-analysis
European Journal of Medical Research
Tai Chi
Parkinson's disease
Lower limbs
Meta-analysis
title Tai Chi improves balance, mobility and gait function of the lower limbs in patients with Parkinson's disease: a systematic review and meta-analysis
title_full Tai Chi improves balance, mobility and gait function of the lower limbs in patients with Parkinson's disease: a systematic review and meta-analysis
title_fullStr Tai Chi improves balance, mobility and gait function of the lower limbs in patients with Parkinson's disease: a systematic review and meta-analysis
title_full_unstemmed Tai Chi improves balance, mobility and gait function of the lower limbs in patients with Parkinson's disease: a systematic review and meta-analysis
title_short Tai Chi improves balance, mobility and gait function of the lower limbs in patients with Parkinson's disease: a systematic review and meta-analysis
title_sort tai chi improves balance mobility and gait function of the lower limbs in patients with parkinson s disease a systematic review and meta analysis
topic Tai Chi
Parkinson's disease
Lower limbs
Meta-analysis
url https://doi.org/10.1186/s40001-024-02151-5
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AT chunyuxiang taichiimprovesbalancemobilityandgaitfunctionofthelowerlimbsinpatientswithparkinsonsdiseaseasystematicreviewandmetaanalysis
AT yinglianghu taichiimprovesbalancemobilityandgaitfunctionofthelowerlimbsinpatientswithparkinsonsdiseaseasystematicreviewandmetaanalysis
AT jiapengyang taichiimprovesbalancemobilityandgaitfunctionofthelowerlimbsinpatientswithparkinsonsdiseaseasystematicreviewandmetaanalysis