Genomic characterization of a multidrug-resistant Citrobacter portucalensis isolate co-harboring blaKPC–2 and blaNDM–1 on distinct plasmids

Genomic characterization of a multidrug-resistant Citrobacter portucalensis isolate co-harboring blaKPC–2 and blaNDM–1 on distinct plasmids

BackgroundCitrobacter portucalensis is an emerging multidrug-resistant (MDR) pathogen within the Citrobacter genus. Although individual occurrences of blaKPC–2 or blaNDM–1 have been sporadically reported, the coexistence of both carbapenemase genes in a single strain remains extremely rare.MethodsWe...

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Bibliographic Details
Main Authors: Junwei Huang, Kai Shen, Keqiang Chen, Junliang Wu, Yijun Zhu, Jingchao Shi
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Microbiology
Subjects:
Citrobacter portucalensis
blaKPC–2
blaNDM–1
plasmid-mediated resistance
antimicrobial resistance
conjugation
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2025.1633493/full
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