The Immune Epitope Database: How Data Are Entered and Retrieved
Easy access to a vast collection of experimental data on immune epitopes can greatly facilitate the development of therapeutics and vaccines. The Immune Epitope Database and Analysis Resource (IEDB) was developed to provide such a resource as a free service to the biomedical research community. The...
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| Format: | Article |
| Language: | English |
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Wiley
2017-01-01
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| Series: | Journal of Immunology Research |
| Online Access: | http://dx.doi.org/10.1155/2017/5974574 |
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| author | Ward Fleri Kerrie Vaughan Nima Salimi Randi Vita Bjoern Peters Alessandro Sette |
| author_facet | Ward Fleri Kerrie Vaughan Nima Salimi Randi Vita Bjoern Peters Alessandro Sette |
| author_sort | Ward Fleri |
| collection | DOAJ |
| description | Easy access to a vast collection of experimental data on immune epitopes can greatly facilitate the development of therapeutics and vaccines. The Immune Epitope Database and Analysis Resource (IEDB) was developed to provide such a resource as a free service to the biomedical research community. The IEDB contains epitope and assay information related to infectious diseases, autoimmune diseases, allergic diseases, and transplant/alloantigens for humans, nonhuman primates, mice, and any other species studied. It contains T cell, B cell, MHC binding, and MHC ligand elution experiments. Its data are curated primarily from the published literature and also include direct submissions from researchers involved in epitope discovery. This article describes the process of capturing data from these sources and how the information is organized in the IEDB data. Different approaches for querying the data are then presented, using the home page search interface and the various specialized search interfaces. Specific examples covering diverse applications of interest are given to highlight the power and functionality of the IEDB. |
| format | Article |
| id | doaj-art-515fe35bfeb4413e945f064bc8ea116a |
| institution | Kabale University |
| issn | 2314-8861 2314-7156 |
| language | English |
| publishDate | 2017-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Immunology Research |
| spelling | doaj-art-515fe35bfeb4413e945f064bc8ea116a2025-08-20T03:36:38ZengWileyJournal of Immunology Research2314-88612314-71562017-01-01201710.1155/2017/59745745974574The Immune Epitope Database: How Data Are Entered and RetrievedWard Fleri0Kerrie Vaughan1Nima Salimi2Randi Vita3Bjoern Peters4Alessandro Sette5Division of Vaccine Discovery, La Jolla Institute for Allergy and Immunology, 9420 Athena Circle, La Jolla, CA 92037, USADivision of Vaccine Discovery, La Jolla Institute for Allergy and Immunology, 9420 Athena Circle, La Jolla, CA 92037, USADivision of Vaccine Discovery, La Jolla Institute for Allergy and Immunology, 9420 Athena Circle, La Jolla, CA 92037, USADivision of Vaccine Discovery, La Jolla Institute for Allergy and Immunology, 9420 Athena Circle, La Jolla, CA 92037, USADivision of Vaccine Discovery, La Jolla Institute for Allergy and Immunology, 9420 Athena Circle, La Jolla, CA 92037, USADivision of Vaccine Discovery, La Jolla Institute for Allergy and Immunology, 9420 Athena Circle, La Jolla, CA 92037, USAEasy access to a vast collection of experimental data on immune epitopes can greatly facilitate the development of therapeutics and vaccines. The Immune Epitope Database and Analysis Resource (IEDB) was developed to provide such a resource as a free service to the biomedical research community. The IEDB contains epitope and assay information related to infectious diseases, autoimmune diseases, allergic diseases, and transplant/alloantigens for humans, nonhuman primates, mice, and any other species studied. It contains T cell, B cell, MHC binding, and MHC ligand elution experiments. Its data are curated primarily from the published literature and also include direct submissions from researchers involved in epitope discovery. This article describes the process of capturing data from these sources and how the information is organized in the IEDB data. Different approaches for querying the data are then presented, using the home page search interface and the various specialized search interfaces. Specific examples covering diverse applications of interest are given to highlight the power and functionality of the IEDB.http://dx.doi.org/10.1155/2017/5974574 |
| spellingShingle | Ward Fleri Kerrie Vaughan Nima Salimi Randi Vita Bjoern Peters Alessandro Sette The Immune Epitope Database: How Data Are Entered and Retrieved Journal of Immunology Research |
| title | The Immune Epitope Database: How Data Are Entered and Retrieved |
| title_full | The Immune Epitope Database: How Data Are Entered and Retrieved |
| title_fullStr | The Immune Epitope Database: How Data Are Entered and Retrieved |
| title_full_unstemmed | The Immune Epitope Database: How Data Are Entered and Retrieved |
| title_short | The Immune Epitope Database: How Data Are Entered and Retrieved |
| title_sort | immune epitope database how data are entered and retrieved |
| url | http://dx.doi.org/10.1155/2017/5974574 |
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