Extracts of Chuanxiong and Baizhi Attenuate Neuroinflammation in Chronic Migraine Rats by Inhibiting TLR4/MyD88/Nuclear Factor Kappa B Signal Pathway

Extracts of Chuanxiong and Baizhi Attenuate Neuroinflammation in Chronic Migraine Rats by Inhibiting TLR4/MyD88/Nuclear Factor Kappa B Signal Pathway

This study investigates the mechanism by which a compound mixture of Chuanxiong and Baizhi (CMCB) modulates the TLR4/MyD88/nuclear factor kappa B (NF-κB) pathway to alleviate neuroinflammation in nitroglycerin (NTG)-induced chronic migraine (CM) rat models. In vivo CM rat models were induced with 10...

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Bibliographic Details
Main Authors: Xin Li, Ting Du, Fan Yang, Chun Ge, Chonghe Yang, Lejun Li
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2025-05-01
Series:Journal of Physiological Investigation
Subjects:
chronic migraine
compound mixture of chuanxiong and baizhi
myd88
neuroinflammation
nuclear factor kappa b
tlr4
Online Access:https://journals.lww.com/jpi/fulltext/2025/05000/extracts_of_chuanxiong_and_baizhi_attenuate.4.aspx
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