Optical Coherence Tomography Angiography in Retinal Vascular Diseases and Choroidal Neovascularization
Purpose. To assess the ability of optical coherence tomography-angiography (OCT-A) to show and analyze retinal vascular patterns and the choroidal neovascularization (CNV) in retinal vascular diseases. Methods. Seven eyes of seven consecutive patients with retinal vascular diseases were examined. Tw...
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| Format: | Article |
| Language: | English |
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Wiley
2015-01-01
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| Series: | Journal of Ophthalmology |
| Online Access: | http://dx.doi.org/10.1155/2015/343515 |
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| author | Rodolfo Mastropasqua Luca Di Antonio Silvio Di Staso Luca Agnifili Angela Di Gregorio Marco Ciancaglini Leonardo Mastropasqua |
| author_facet | Rodolfo Mastropasqua Luca Di Antonio Silvio Di Staso Luca Agnifili Angela Di Gregorio Marco Ciancaglini Leonardo Mastropasqua |
| author_sort | Rodolfo Mastropasqua |
| collection | DOAJ |
| description | Purpose. To assess the ability of optical coherence tomography-angiography (OCT-A) to show and analyze retinal vascular patterns and the choroidal neovascularization (CNV) in retinal vascular diseases. Methods. Seven eyes of seven consecutive patients with retinal vascular diseases were examined. Two healthy subjects served as controls. All eyes were scanned with the SD-OCT XR Avanti (Optovue Inc, Fremont CA, USA). Split spectrum amplitude decorrelation angiography algorithm was used to identify the blood flow within the tissue. Fluorescein angiography (FA) and indocyanine green angiography (ICGA) with Spectralis HRA + OCT (Heidelberg Engineering GmbH) were performed. Results. In healthy subjects OCT-A visualized major macular vessels and detailed capillary networks around the foveal avascular zone. Patients were affected with myopic CNV (2 eyes), age-related macular degeneration related (2), branch retinal vein occlusion (BRVO) (2), and branch retinal artery occlusion (BRAO) (1). OCT-A images provided distinct vascular patterns, distinguishing perfused and nonperfused areas in BRVO and BRAO and recognizing the presence, location, and size of CNV. Conclusions. OCT-A provides detailed images of retinal vascular plexuses and quantitative data of pathologic structures. Further studies are warranted to define the role of OCT-A in the assessment of retinovascular diseases, with respect to conventional FA and ICG-A. |
| format | Article |
| id | doaj-art-514dc43b373f402c8f0225e4792b1727 |
| institution | Kabale University |
| issn | 2090-004X 2090-0058 |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Ophthalmology |
| spelling | doaj-art-514dc43b373f402c8f0225e4792b17272025-02-03T05:47:30ZengWileyJournal of Ophthalmology2090-004X2090-00582015-01-01201510.1155/2015/343515343515Optical Coherence Tomography Angiography in Retinal Vascular Diseases and Choroidal NeovascularizationRodolfo Mastropasqua0Luca Di Antonio1Silvio Di Staso2Luca Agnifili3Angela Di Gregorio4Marco Ciancaglini5Leonardo Mastropasqua6Ophthalmology Unit, Department of Neurological, Neuropsychological, Morphological and Movement Sciences, University of Verona, 37100 Verona, ItalyOphthalmology Clinic, Department of Medicine and Aging Science, University G. d’Annunzio of Chieti-Pescara, 66100 Chieti, ItalyEye Clinic, Department of Life, Health and Environmental Sciences, University of L’Aquila, 67100 L’Aquila, ItalyOphthalmology Clinic, Department of Medicine and Aging Science, University G. d’Annunzio of Chieti-Pescara, 66100 Chieti, ItalyEye Clinic, Department of Life, Health and Environmental Sciences, University of L’Aquila, 67100 L’Aquila, ItalyEye Clinic, Department of Life, Health and Environmental Sciences, University of L’Aquila, 67100 L’Aquila, ItalyOphthalmology Clinic, Department of Medicine and Aging Science, University G. d’Annunzio of Chieti-Pescara, 66100 Chieti, ItalyPurpose. To assess the ability of optical coherence tomography-angiography (OCT-A) to show and analyze retinal vascular patterns and the choroidal neovascularization (CNV) in retinal vascular diseases. Methods. Seven eyes of seven consecutive patients with retinal vascular diseases were examined. Two healthy subjects served as controls. All eyes were scanned with the SD-OCT XR Avanti (Optovue Inc, Fremont CA, USA). Split spectrum amplitude decorrelation angiography algorithm was used to identify the blood flow within the tissue. Fluorescein angiography (FA) and indocyanine green angiography (ICGA) with Spectralis HRA + OCT (Heidelberg Engineering GmbH) were performed. Results. In healthy subjects OCT-A visualized major macular vessels and detailed capillary networks around the foveal avascular zone. Patients were affected with myopic CNV (2 eyes), age-related macular degeneration related (2), branch retinal vein occlusion (BRVO) (2), and branch retinal artery occlusion (BRAO) (1). OCT-A images provided distinct vascular patterns, distinguishing perfused and nonperfused areas in BRVO and BRAO and recognizing the presence, location, and size of CNV. Conclusions. OCT-A provides detailed images of retinal vascular plexuses and quantitative data of pathologic structures. Further studies are warranted to define the role of OCT-A in the assessment of retinovascular diseases, with respect to conventional FA and ICG-A.http://dx.doi.org/10.1155/2015/343515 |
| spellingShingle | Rodolfo Mastropasqua Luca Di Antonio Silvio Di Staso Luca Agnifili Angela Di Gregorio Marco Ciancaglini Leonardo Mastropasqua Optical Coherence Tomography Angiography in Retinal Vascular Diseases and Choroidal Neovascularization Journal of Ophthalmology |
| title | Optical Coherence Tomography Angiography in Retinal Vascular Diseases and Choroidal Neovascularization |
| title_full | Optical Coherence Tomography Angiography in Retinal Vascular Diseases and Choroidal Neovascularization |
| title_fullStr | Optical Coherence Tomography Angiography in Retinal Vascular Diseases and Choroidal Neovascularization |
| title_full_unstemmed | Optical Coherence Tomography Angiography in Retinal Vascular Diseases and Choroidal Neovascularization |
| title_short | Optical Coherence Tomography Angiography in Retinal Vascular Diseases and Choroidal Neovascularization |
| title_sort | optical coherence tomography angiography in retinal vascular diseases and choroidal neovascularization |
| url | http://dx.doi.org/10.1155/2015/343515 |
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