Anthropogenically driven environmental changes shift the ecological dynamics of hemorrhagic fever with renal syndrome.

Zoonoses are increasingly recognized as an important burden on global public health in the 21st century. High-resolution, long-term field studies are critical for assessing both the baseline and future risk scenarios in a world of rapid changes. We have used a three-decade-long field study on hantav...

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Main Authors: Huaiyu Tian, Pengbo Yu, Ottar N Bjørnstad, Bernard Cazelles, Jing Yang, Hua Tan, Shanqian Huang, Yujun Cui, Lu Dong, Chaofeng Ma, Changan Ma, Sen Zhou, Marko Laine, Xiaoxu Wu, Yanyun Zhang, Jingjun Wang, Ruifu Yang, Nils Chr Stenseth, Bing Xu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS Pathogens
Online Access:https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1006198&type=printable
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author Huaiyu Tian
Pengbo Yu
Ottar N Bjørnstad
Bernard Cazelles
Jing Yang
Hua Tan
Shanqian Huang
Yujun Cui
Lu Dong
Chaofeng Ma
Changan Ma
Sen Zhou
Marko Laine
Xiaoxu Wu
Yanyun Zhang
Jingjun Wang
Ruifu Yang
Nils Chr Stenseth
Bing Xu
author_facet Huaiyu Tian
Pengbo Yu
Ottar N Bjørnstad
Bernard Cazelles
Jing Yang
Hua Tan
Shanqian Huang
Yujun Cui
Lu Dong
Chaofeng Ma
Changan Ma
Sen Zhou
Marko Laine
Xiaoxu Wu
Yanyun Zhang
Jingjun Wang
Ruifu Yang
Nils Chr Stenseth
Bing Xu
author_sort Huaiyu Tian
collection DOAJ
description Zoonoses are increasingly recognized as an important burden on global public health in the 21st century. High-resolution, long-term field studies are critical for assessing both the baseline and future risk scenarios in a world of rapid changes. We have used a three-decade-long field study on hantavirus, a rodent-borne zoonotic pathogen distributed worldwide, coupled with epidemiological data from an endemic area of China, and show that the shift in the ecological dynamics of Hantaan virus was closely linked to environmental fluctuations at the human-wildlife interface. We reveal that environmental forcing, especially rainfall and resource availability, exert important cascading effects on intra-annual variability in the wildlife reservoir dynamics, leading to epidemics that shift between stable and chaotic regimes. Our models demonstrate that bimodal seasonal epidemics result from a powerful seasonality in transmission, generated from interlocking cycles of agricultural phenology and rodent behavior driven by the rainy seasons.
format Article
id doaj-art-514b5ca415bb408f95d287d74007c176
institution DOAJ
issn 1553-7366
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language English
publishDate 2017-01-01
publisher Public Library of Science (PLoS)
record_format Article
series PLoS Pathogens
spelling doaj-art-514b5ca415bb408f95d287d74007c1762025-08-20T02:45:28ZengPublic Library of Science (PLoS)PLoS Pathogens1553-73661553-73742017-01-01131e100619810.1371/journal.ppat.1006198Anthropogenically driven environmental changes shift the ecological dynamics of hemorrhagic fever with renal syndrome.Huaiyu TianPengbo YuOttar N BjørnstadBernard CazellesJing YangHua TanShanqian HuangYujun CuiLu DongChaofeng MaChangan MaSen ZhouMarko LaineXiaoxu WuYanyun ZhangJingjun WangRuifu YangNils Chr StensethBing XuZoonoses are increasingly recognized as an important burden on global public health in the 21st century. High-resolution, long-term field studies are critical for assessing both the baseline and future risk scenarios in a world of rapid changes. We have used a three-decade-long field study on hantavirus, a rodent-borne zoonotic pathogen distributed worldwide, coupled with epidemiological data from an endemic area of China, and show that the shift in the ecological dynamics of Hantaan virus was closely linked to environmental fluctuations at the human-wildlife interface. We reveal that environmental forcing, especially rainfall and resource availability, exert important cascading effects on intra-annual variability in the wildlife reservoir dynamics, leading to epidemics that shift between stable and chaotic regimes. Our models demonstrate that bimodal seasonal epidemics result from a powerful seasonality in transmission, generated from interlocking cycles of agricultural phenology and rodent behavior driven by the rainy seasons.https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1006198&type=printable
spellingShingle Huaiyu Tian
Pengbo Yu
Ottar N Bjørnstad
Bernard Cazelles
Jing Yang
Hua Tan
Shanqian Huang
Yujun Cui
Lu Dong
Chaofeng Ma
Changan Ma
Sen Zhou
Marko Laine
Xiaoxu Wu
Yanyun Zhang
Jingjun Wang
Ruifu Yang
Nils Chr Stenseth
Bing Xu
Anthropogenically driven environmental changes shift the ecological dynamics of hemorrhagic fever with renal syndrome.
PLoS Pathogens
title Anthropogenically driven environmental changes shift the ecological dynamics of hemorrhagic fever with renal syndrome.
title_full Anthropogenically driven environmental changes shift the ecological dynamics of hemorrhagic fever with renal syndrome.
title_fullStr Anthropogenically driven environmental changes shift the ecological dynamics of hemorrhagic fever with renal syndrome.
title_full_unstemmed Anthropogenically driven environmental changes shift the ecological dynamics of hemorrhagic fever with renal syndrome.
title_short Anthropogenically driven environmental changes shift the ecological dynamics of hemorrhagic fever with renal syndrome.
title_sort anthropogenically driven environmental changes shift the ecological dynamics of hemorrhagic fever with renal syndrome
url https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1006198&type=printable
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