Biological and pharmacological roles of pyroptosis in pulmonary inflammation and fibrosis: recent advances and future directions

Biological and pharmacological roles of pyroptosis in pulmonary inflammation and fibrosis: recent advances and future directions

Abstract Pyroptosis, an inflammatory regulated cell death (RCD) mechanism, is characterized by cellular swelling, membrane rupture, and subsequent discharge of cellular contents, exerting robust proinflammatory effects. Recent studies have significantly advanced our understanding of pyroptosis, reve...

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Bibliographic Details
Main Authors: Ya Liu, Danxia Wang, Xiang Liu, Haibin Yuan, Dan Liu, Yixiang Hu, Shipeng Ning
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Cell Communication and Signaling
Subjects:
Pulmonary fibrosis
Pyroptosis
Inflammation
Gasdermin
Inflammasome
Online Access:https://doi.org/10.1186/s12964-024-01966-3
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