Evaluation of transition rates from nonequilibrium instantons

Equilibrium rate theories play a crucial role in understanding rare, reactive events. However, they are inapplicable to a range of irreversible processes in systems driven far from thermodynamic equilibrium like active and biological matter. Here we develop an efficient numerical method to compute t...

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Main Authors: Eric R. Heller, David T. Limmer
Format: Article
Language:English
Published: American Physical Society 2024-11-01
Series:Physical Review Research
Online Access:http://doi.org/10.1103/PhysRevResearch.6.043110
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author Eric R. Heller
David T. Limmer
author_facet Eric R. Heller
David T. Limmer
author_sort Eric R. Heller
collection DOAJ
description Equilibrium rate theories play a crucial role in understanding rare, reactive events. However, they are inapplicable to a range of irreversible processes in systems driven far from thermodynamic equilibrium like active and biological matter. Here we develop an efficient numerical method to compute the rate constant of rare nonequilibrium events in the weak-noise limit based on an instanton approximation to the stochastic path integral and illustrate its wide range of application. We demonstrate excellent agreement of the instanton rates with numerically exact results for a particle under a nonconservative force. We also study phase transitions in an active field theory. We elucidate how activity alters the stability of the two phases and their rates of interconversion in a manner that can be well described by modifying classical nucleation theory.
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spelling doaj-art-51473e05ca6a4576a7879882b2188fcd2025-08-20T02:12:34ZengAmerican Physical SocietyPhysical Review Research2643-15642024-11-016404311010.1103/PhysRevResearch.6.043110Evaluation of transition rates from nonequilibrium instantonsEric R. HellerDavid T. LimmerEquilibrium rate theories play a crucial role in understanding rare, reactive events. However, they are inapplicable to a range of irreversible processes in systems driven far from thermodynamic equilibrium like active and biological matter. Here we develop an efficient numerical method to compute the rate constant of rare nonequilibrium events in the weak-noise limit based on an instanton approximation to the stochastic path integral and illustrate its wide range of application. We demonstrate excellent agreement of the instanton rates with numerically exact results for a particle under a nonconservative force. We also study phase transitions in an active field theory. We elucidate how activity alters the stability of the two phases and their rates of interconversion in a manner that can be well described by modifying classical nucleation theory.http://doi.org/10.1103/PhysRevResearch.6.043110
spellingShingle Eric R. Heller
David T. Limmer
Evaluation of transition rates from nonequilibrium instantons
Physical Review Research
title Evaluation of transition rates from nonequilibrium instantons
title_full Evaluation of transition rates from nonequilibrium instantons
title_fullStr Evaluation of transition rates from nonequilibrium instantons
title_full_unstemmed Evaluation of transition rates from nonequilibrium instantons
title_short Evaluation of transition rates from nonequilibrium instantons
title_sort evaluation of transition rates from nonequilibrium instantons
url http://doi.org/10.1103/PhysRevResearch.6.043110
work_keys_str_mv AT ericrheller evaluationoftransitionratesfromnonequilibriuminstantons
AT davidtlimmer evaluationoftransitionratesfromnonequilibriuminstantons