First case report of bacteremia caused by Bilophila wadsworthia in China, and literature review
Abstract Bilophila wadsworthia is rarely found in the bloodstream. We report the first case of bloodstream infection caused by B. wadsworthia in a diabetic foot patient in China. B. wadsworthia is a normal component of the human intestinal microbiota, and a history of diarrhea may contribute to its...
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| Format: | Article |
| Language: | English |
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BMC
2025-02-01
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| Series: | BMC Infectious Diseases |
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| Online Access: | https://doi.org/10.1186/s12879-025-10570-w |
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| author | Fangrong Gan Shuang Luo Xiaoxun Wei Shuguang Zuo |
| author_facet | Fangrong Gan Shuang Luo Xiaoxun Wei Shuguang Zuo |
| author_sort | Fangrong Gan |
| collection | DOAJ |
| description | Abstract Bilophila wadsworthia is rarely found in the bloodstream. We report the first case of bloodstream infection caused by B. wadsworthia in a diabetic foot patient in China. B. wadsworthia is a normal component of the human intestinal microbiota, and a history of diarrhea may contribute to its translocation into the bloodstream. Due to the slow growth of B. wadsworthia, prolonged incubation was essential for its detection. Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) enabled rapid identification of the pathogen. Early initiation of Piperacillin/Tazobactam therapy resulted in a favorable clinical outcome. |
| format | Article |
| id | doaj-art-5143613a96494263985c87ea7109ab78 |
| institution | Kabale University |
| issn | 1471-2334 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Infectious Diseases |
| spelling | doaj-art-5143613a96494263985c87ea7109ab782025-02-09T12:14:36ZengBMCBMC Infectious Diseases1471-23342025-02-012511510.1186/s12879-025-10570-wFirst case report of bacteremia caused by Bilophila wadsworthia in China, and literature reviewFangrong Gan0Shuang Luo1Xiaoxun Wei2Shuguang Zuo3Department of clinical laboratory, LiuZhou Municipal Liutie Central HospitalDepartment of clinical laboratory, LiuZhou Municipal Liutie Central HospitalDepartment of clinical laboratory, LiuZhou Municipal Liutie Central HospitalDepartment of clinical laboratory, LiuZhou Municipal Liutie Central HospitalAbstract Bilophila wadsworthia is rarely found in the bloodstream. We report the first case of bloodstream infection caused by B. wadsworthia in a diabetic foot patient in China. B. wadsworthia is a normal component of the human intestinal microbiota, and a history of diarrhea may contribute to its translocation into the bloodstream. Due to the slow growth of B. wadsworthia, prolonged incubation was essential for its detection. Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) enabled rapid identification of the pathogen. Early initiation of Piperacillin/Tazobactam therapy resulted in a favorable clinical outcome.https://doi.org/10.1186/s12879-025-10570-wAnaerobic bacteremiaBilophila wadsworthiaMALDI-TOF MS |
| spellingShingle | Fangrong Gan Shuang Luo Xiaoxun Wei Shuguang Zuo First case report of bacteremia caused by Bilophila wadsworthia in China, and literature review BMC Infectious Diseases Anaerobic bacteremia Bilophila wadsworthia MALDI-TOF MS |
| title | First case report of bacteremia caused by Bilophila wadsworthia in China, and literature review |
| title_full | First case report of bacteremia caused by Bilophila wadsworthia in China, and literature review |
| title_fullStr | First case report of bacteremia caused by Bilophila wadsworthia in China, and literature review |
| title_full_unstemmed | First case report of bacteremia caused by Bilophila wadsworthia in China, and literature review |
| title_short | First case report of bacteremia caused by Bilophila wadsworthia in China, and literature review |
| title_sort | first case report of bacteremia caused by bilophila wadsworthia in china and literature review |
| topic | Anaerobic bacteremia Bilophila wadsworthia MALDI-TOF MS |
| url | https://doi.org/10.1186/s12879-025-10570-w |
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