Ultrasound monitoring of hidradenitis suppurativa fistulas in treatment with adalimumab
Recently, ultrasound has become a significant tool in studying hidradenitis suppurativa (HS), allowing differentiation between abscesses and fistulas, and assessing various disease features. However, there is still a lack of data on using ultrasound (US) to assess treatment response to medical trea...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
PAGEPress Publications
2025-04-01
|
| Series: | Dermatology Reports |
| Subjects: | |
| Online Access: | https://www.pagepress.org/journals/dr/article/view/10124 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849769645395935232 |
|---|---|
| author | Raffaele Dante Caposiena Caro Giulia Bazzacco Enrico Zelin Vanessa Mazzoletti Nicola Di Meo Iris Zalaudek |
| author_facet | Raffaele Dante Caposiena Caro Giulia Bazzacco Enrico Zelin Vanessa Mazzoletti Nicola Di Meo Iris Zalaudek |
| author_sort | Raffaele Dante Caposiena Caro |
| collection | DOAJ |
| description |
Recently, ultrasound has become a significant tool in studying hidradenitis suppurativa (HS), allowing differentiation between abscesses and fistulas, and assessing various disease features. However, there is still a lack of data on using ultrasound (US) to assess treatment response to medical treatment. The study aims to assess the clinical usefulness of ultrasound in monitoring disease activity in HS patients undergoing treatment with adalimumab over a 52-week period. This research employs a retrospective approach to analyze ultrasound scores related to fibrosis, edema, power-Doppler (PD) signal, and resistive index (RI) at baseline and after 52 weeks of adalimumab treatment. In total, 311 fistulas from 69 patients were included. Multivariate regression analysis showed that PD score and edema were related to IHS4-55 and variations of DLQI and pain-VAS. Furthermore, at baseline, healed and non-healed fistulas were characterized by significant differences in PD signal, fibrosis, edema, and RI. Limitations include the retrospective design of the study, a limited population size, and the absence of a control group. However, our data provide evidence that ultrasound can be a reliable tool for assessing patients’ responses to medical therapies.
|
| format | Article |
| id | doaj-art-5123ad71abdc4b7cb68d24a16dc72299 |
| institution | DOAJ |
| issn | 2036-7392 2036-7406 |
| language | English |
| publishDate | 2025-04-01 |
| publisher | PAGEPress Publications |
| record_format | Article |
| series | Dermatology Reports |
| spelling | doaj-art-5123ad71abdc4b7cb68d24a16dc722992025-08-20T03:03:21ZengPAGEPress PublicationsDermatology Reports2036-73922036-74062025-04-0110.4081/dr.2025.10124Ultrasound monitoring of hidradenitis suppurativa fistulas in treatment with adalimumabRaffaele Dante Caposiena Caro0Giulia Bazzacco1Enrico Zelin2Vanessa Mazzoletti3Nicola Di Meo4Iris Zalaudek5Dermatology Clinic, Hospital Maggiore of Trieste, University of TriesteInstitute of Dermatology, Santa Maria della Misericordia University Hospital, UdineInstitute of Dermatology, Santa Maria della Misericordia University Hospital, UdineInstitute of Dermatology, Santa Maria della Misericordia University Hospital, UdineDermatology Clinic, Hospital Maggiore of Trieste, University of TriesteDermatology Clinic, Hospital Maggiore of Trieste, University of Trieste Recently, ultrasound has become a significant tool in studying hidradenitis suppurativa (HS), allowing differentiation between abscesses and fistulas, and assessing various disease features. However, there is still a lack of data on using ultrasound (US) to assess treatment response to medical treatment. The study aims to assess the clinical usefulness of ultrasound in monitoring disease activity in HS patients undergoing treatment with adalimumab over a 52-week period. This research employs a retrospective approach to analyze ultrasound scores related to fibrosis, edema, power-Doppler (PD) signal, and resistive index (RI) at baseline and after 52 weeks of adalimumab treatment. In total, 311 fistulas from 69 patients were included. Multivariate regression analysis showed that PD score and edema were related to IHS4-55 and variations of DLQI and pain-VAS. Furthermore, at baseline, healed and non-healed fistulas were characterized by significant differences in PD signal, fibrosis, edema, and RI. Limitations include the retrospective design of the study, a limited population size, and the absence of a control group. However, our data provide evidence that ultrasound can be a reliable tool for assessing patients’ responses to medical therapies. https://www.pagepress.org/journals/dr/article/view/10124Hidradenitis suppurativaultrasoundadalimumab |
| spellingShingle | Raffaele Dante Caposiena Caro Giulia Bazzacco Enrico Zelin Vanessa Mazzoletti Nicola Di Meo Iris Zalaudek Ultrasound monitoring of hidradenitis suppurativa fistulas in treatment with adalimumab Dermatology Reports Hidradenitis suppurativa ultrasound adalimumab |
| title | Ultrasound monitoring of hidradenitis suppurativa fistulas in treatment with adalimumab |
| title_full | Ultrasound monitoring of hidradenitis suppurativa fistulas in treatment with adalimumab |
| title_fullStr | Ultrasound monitoring of hidradenitis suppurativa fistulas in treatment with adalimumab |
| title_full_unstemmed | Ultrasound monitoring of hidradenitis suppurativa fistulas in treatment with adalimumab |
| title_short | Ultrasound monitoring of hidradenitis suppurativa fistulas in treatment with adalimumab |
| title_sort | ultrasound monitoring of hidradenitis suppurativa fistulas in treatment with adalimumab |
| topic | Hidradenitis suppurativa ultrasound adalimumab |
| url | https://www.pagepress.org/journals/dr/article/view/10124 |
| work_keys_str_mv | AT raffaeledantecaposienacaro ultrasoundmonitoringofhidradenitissuppurativafistulasintreatmentwithadalimumab AT giuliabazzacco ultrasoundmonitoringofhidradenitissuppurativafistulasintreatmentwithadalimumab AT enricozelin ultrasoundmonitoringofhidradenitissuppurativafistulasintreatmentwithadalimumab AT vanessamazzoletti ultrasoundmonitoringofhidradenitissuppurativafistulasintreatmentwithadalimumab AT nicoladimeo ultrasoundmonitoringofhidradenitissuppurativafistulasintreatmentwithadalimumab AT iriszalaudek ultrasoundmonitoringofhidradenitissuppurativafistulasintreatmentwithadalimumab |