Pooling data for primary total knee implants across national registries: is the same implant used in multiple registries and for the same patient group? An observational study

Background and purpose: Pooling data on the performance of total knee (TK) implants across registries is only possible if the same TK implant is used across multiple registries and if used in patients with similar characteristics. We assessed to what extent specific TK implants: (i) are used across...

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Main Authors: Lotje Hoogervorst, Rob G H H Nelissen, Liza van Steenbergen, Alma B Pedersen, Eskild Bendix Kristiansen, Martin Lindberg-Larsen, Marina Torre, Enrico Ciminello, Riccardo Valentini, Alexander W Grimberg, Yinan Wu, Perla J Marang-van de Mheen
Format: Article
Language:English
Published: Medical Journals Sweden 2025-04-01
Series:Acta Orthopaedica
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Online Access:https://actaorthop.org/actao/article/view/43476
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author Lotje Hoogervorst
Rob G H H Nelissen
Liza van Steenbergen
Alma B Pedersen
Eskild Bendix Kristiansen
Martin Lindberg-Larsen
Marina Torre
Enrico Ciminello
Riccardo Valentini
Alexander W Grimberg
Yinan Wu
Perla J Marang-van de Mheen
author_facet Lotje Hoogervorst
Rob G H H Nelissen
Liza van Steenbergen
Alma B Pedersen
Eskild Bendix Kristiansen
Martin Lindberg-Larsen
Marina Torre
Enrico Ciminello
Riccardo Valentini
Alexander W Grimberg
Yinan Wu
Perla J Marang-van de Mheen
author_sort Lotje Hoogervorst
collection DOAJ
description Background and purpose: Pooling data on the performance of total knee (TK) implants across registries is only possible if the same TK implant is used across multiple registries and if used in patients with similar characteristics. We assessed to what extent specific TK implants: (i) are used across multiple registries or only in a single registry; and (ii) differ in patient characteristics between registries. Methods: All primary TK implants implanted between January 2020 and December 2021 in the Danish, Dutch, German, and Italian registries were included. We determined the number of registries using a specific TK implant (based on combined femoral-tibial component brand name and fixation/congruency/mobile bearing insert/patella usage). Patient characteristics (age/body mass index [BMI]/sex/diagnosis osteoarthritis) were compared across registries for TK implants used in ≥ 2 registries ≥ 100 times. Results: 813 different TK implants (577,351 procedures) were used across the 4 registries, of which 53 TK implants (7%) were used in 1 registry (8,000 procedures). 760 different TK implants (569,351 procedures; 99%) were used in ≥ 2 registries of which 47 different TK implants (393,954 procedures; 68%) were used in ≥ 2 registries and ≥ 100 times. Statistically and clinically significant differences in age for the same TK implant across registries were observed for 29 TK implants (62%) and 3 TK implants (6%), respectively; for other characteristics these were for BMI 30 (64%) and 0 (0%) TK implants; for male proportion 23 (49%) and 17 (36%) TK implants; and for diagnosis of osteoarthritis 42 (89%) and 34 (72%) TK implants, respectively. Conclusion: Most specific TK implants and TK procedures were used across multiple registries, but they were often used in patients with different characteristics. This has an impact on comparing implant performances between registries.
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spelling doaj-art-511b529892cc4889a045309f574b0c5f2025-08-20T03:18:05ZengMedical Journals SwedenActa Orthopaedica1745-36741745-36822025-04-019610.2340/17453674.2025.43476Pooling data for primary total knee implants across national registries: is the same implant used in multiple registries and for the same patient group? An observational studyLotje Hoogervorst0https://orcid.org/0000-0001-5343-6965Rob G H H Nelissen1https://orcid.org/0000-0003-1228-4162Liza van Steenbergen2https://orcid.org/0000-0002-8141-842XAlma B Pedersen3https://orcid.org/0000-0002-3288-9401Eskild Bendix Kristiansen4Martin Lindberg-Larsen5https://orcid.org/0000-0002-4483-677XMarina Torre6https://orcid.org/0000-0003-3851-187XEnrico Ciminello7Riccardo Valentini8Alexander W Grimberg9https://orcid.org/0000-0001-8062-788XYinan Wu10Perla J Marang-van de Mheen11Department of Orthopaedics, Leiden University Medical Center, Leiden, the NetherlandsDepartment of Orthopaedics, Leiden University Medical Center, Leiden, the NetherlandsDutch Arthroplasty Register (LROI), ‘s- Hertogenbosch, the NetherlandsDepartment of Clinical Epidemiology, Aarhus University Hospital, Aarhus; Department of Clinical Medicine, Aarhus University, Aarhus, DenmarkDepartment of Clinical Epidemiology, Aarhus University Hospital, Aarhus, DenmarkThe Danish Knee Arthroplasty Register; Department of Orthopedic Surgery and Traumatology, Odense University Hospital, Odense, DenmarkItalian Implantable Prostheses Registry, Italian National Institute of Health, Rome, ItalyItalian Implantable Prostheses Registry, Italian National Institute of Health, Rome, ItalyItalian Implantable Prostheses Registry, Italian National Institute of Health, Rome, ItalyGerman Arthroplasty Registry – EPRD, Berlin, GermanyGerman Arthroplasty Registry – EPRD, Berlin, GermanyDepartment of Orthopaedics, Leiden University Medical Center, Leiden; Safety & Security Science and Centre for Safety in Healthcare, Delft University of Technology, Delft, the Netherlands Background and purpose: Pooling data on the performance of total knee (TK) implants across registries is only possible if the same TK implant is used across multiple registries and if used in patients with similar characteristics. We assessed to what extent specific TK implants: (i) are used across multiple registries or only in a single registry; and (ii) differ in patient characteristics between registries. Methods: All primary TK implants implanted between January 2020 and December 2021 in the Danish, Dutch, German, and Italian registries were included. We determined the number of registries using a specific TK implant (based on combined femoral-tibial component brand name and fixation/congruency/mobile bearing insert/patella usage). Patient characteristics (age/body mass index [BMI]/sex/diagnosis osteoarthritis) were compared across registries for TK implants used in ≥ 2 registries ≥ 100 times. Results: 813 different TK implants (577,351 procedures) were used across the 4 registries, of which 53 TK implants (7%) were used in 1 registry (8,000 procedures). 760 different TK implants (569,351 procedures; 99%) were used in ≥ 2 registries of which 47 different TK implants (393,954 procedures; 68%) were used in ≥ 2 registries and ≥ 100 times. Statistically and clinically significant differences in age for the same TK implant across registries were observed for 29 TK implants (62%) and 3 TK implants (6%), respectively; for other characteristics these were for BMI 30 (64%) and 0 (0%) TK implants; for male proportion 23 (49%) and 17 (36%) TK implants; and for diagnosis of osteoarthritis 42 (89%) and 34 (72%) TK implants, respectively. Conclusion: Most specific TK implants and TK procedures were used across multiple registries, but they were often used in patients with different characteristics. This has an impact on comparing implant performances between registries. https://actaorthop.org/actao/article/view/43476ImplantsKnee
spellingShingle Lotje Hoogervorst
Rob G H H Nelissen
Liza van Steenbergen
Alma B Pedersen
Eskild Bendix Kristiansen
Martin Lindberg-Larsen
Marina Torre
Enrico Ciminello
Riccardo Valentini
Alexander W Grimberg
Yinan Wu
Perla J Marang-van de Mheen
Pooling data for primary total knee implants across national registries: is the same implant used in multiple registries and for the same patient group? An observational study
Acta Orthopaedica
Implants
Knee
title Pooling data for primary total knee implants across national registries: is the same implant used in multiple registries and for the same patient group? An observational study
title_full Pooling data for primary total knee implants across national registries: is the same implant used in multiple registries and for the same patient group? An observational study
title_fullStr Pooling data for primary total knee implants across national registries: is the same implant used in multiple registries and for the same patient group? An observational study
title_full_unstemmed Pooling data for primary total knee implants across national registries: is the same implant used in multiple registries and for the same patient group? An observational study
title_short Pooling data for primary total knee implants across national registries: is the same implant used in multiple registries and for the same patient group? An observational study
title_sort pooling data for primary total knee implants across national registries is the same implant used in multiple registries and for the same patient group an observational study
topic Implants
Knee
url https://actaorthop.org/actao/article/view/43476
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