Genetic diversity of East European and Asian strains of tick-borne encephalitis virus belonging to Siberian genotype
We have studied 40 strains of tick-borne encephalitis virus attributed to Siberian genotype. The fragment of E gene (211 nt) has been sequenced for all strains. Futher analysis has evidenced the formation of two clusters. One of them includes the strains of East European (EE) origin, the other compr...
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| Language: | English |
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Siberian State Medical University (Tomsk)
2006-12-01
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| Series: | Бюллетень сибирской медицины |
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| Online Access: | https://bulletin.ssmu.ru/jour/article/view/3193 |
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| author | L. S. Karan V. V. Pogodina T. V. Frolova A. Ye. Platonov |
| author_facet | L. S. Karan V. V. Pogodina T. V. Frolova A. Ye. Platonov |
| author_sort | L. S. Karan |
| collection | DOAJ |
| description | We have studied 40 strains of tick-borne encephalitis virus attributed to Siberian genotype. The fragment of E gene (211 nt) has been sequenced for all strains. Futher analysis has evidenced the formation of two clusters. One of them includes the strains of East European (EE) origin, the other comprises the strains of Asian origin (A). 17 of 20 East European strains have histidin (H) in amino acid position 234 of gene E, the remaining 3 have either glutamine (Q) or tyrosine (Y). 13 Asian strains have histidine and 7 Asian strains have glutamine in amino acid position 234. |
| format | Article |
| id | doaj-art-5111ef47e2b14d27b40c24b87677da92 |
| institution | Kabale University |
| issn | 1682-0363 1819-3684 |
| language | English |
| publishDate | 2006-12-01 |
| publisher | Siberian State Medical University (Tomsk) |
| record_format | Article |
| series | Бюллетень сибирской медицины |
| spelling | doaj-art-5111ef47e2b14d27b40c24b87677da922025-08-20T04:00:18ZengSiberian State Medical University (Tomsk)Бюллетень сибирской медицины1682-03631819-36842006-12-0150243510.20538/1682-0363-2006--24-351849Genetic diversity of East European and Asian strains of tick-borne encephalitis virus belonging to Siberian genotypeL. S. Karan0V. V. Pogodina1T. V. Frolova2A. Ye. Platonov3Центральный НИИ эпидемиологии РоспотребнадзораИнститут полиомиелита и вирусных энцефалитов им. М.П. Чумакова РАМНИнститут полиомиелита и вирусных энцефалитов им. М.П. Чумакова РАМНЦентральный НИИ эпидемиологии РоспотребнадзораWe have studied 40 strains of tick-borne encephalitis virus attributed to Siberian genotype. The fragment of E gene (211 nt) has been sequenced for all strains. Futher analysis has evidenced the formation of two clusters. One of them includes the strains of East European (EE) origin, the other comprises the strains of Asian origin (A). 17 of 20 East European strains have histidin (H) in amino acid position 234 of gene E, the remaining 3 have either glutamine (Q) or tyrosine (Y). 13 Asian strains have histidine and 7 Asian strains have glutamine in amino acid position 234.https://bulletin.ssmu.ru/jour/article/view/3193вирус клещевого энцефалитасибирский генотипвосточноевропейская и азиатская популяциисе- квенированиеtick-borne encephalitis virussiberian genotypeeast european and asian populationssequencing |
| spellingShingle | L. S. Karan V. V. Pogodina T. V. Frolova A. Ye. Platonov Genetic diversity of East European and Asian strains of tick-borne encephalitis virus belonging to Siberian genotype Бюллетень сибирской медицины вирус клещевого энцефалита сибирский генотип восточноевропейская и азиатская популяции се- квенирование tick-borne encephalitis virus siberian genotype east european and asian populations sequencing |
| title | Genetic diversity of East European and Asian strains of tick-borne encephalitis virus belonging to Siberian genotype |
| title_full | Genetic diversity of East European and Asian strains of tick-borne encephalitis virus belonging to Siberian genotype |
| title_fullStr | Genetic diversity of East European and Asian strains of tick-borne encephalitis virus belonging to Siberian genotype |
| title_full_unstemmed | Genetic diversity of East European and Asian strains of tick-borne encephalitis virus belonging to Siberian genotype |
| title_short | Genetic diversity of East European and Asian strains of tick-borne encephalitis virus belonging to Siberian genotype |
| title_sort | genetic diversity of east european and asian strains of tick borne encephalitis virus belonging to siberian genotype |
| topic | вирус клещевого энцефалита сибирский генотип восточноевропейская и азиатская популяции се- квенирование tick-borne encephalitis virus siberian genotype east european and asian populations sequencing |
| url | https://bulletin.ssmu.ru/jour/article/view/3193 |
| work_keys_str_mv | AT lskaran geneticdiversityofeasteuropeanandasianstrainsoftickborneencephalitisvirusbelongingtosiberiangenotype AT vvpogodina geneticdiversityofeasteuropeanandasianstrainsoftickborneencephalitisvirusbelongingtosiberiangenotype AT tvfrolova geneticdiversityofeasteuropeanandasianstrainsoftickborneencephalitisvirusbelongingtosiberiangenotype AT ayeplatonov geneticdiversityofeasteuropeanandasianstrainsoftickborneencephalitisvirusbelongingtosiberiangenotype |