MicroRNA MiR-21 and MiR-155 are new markers for breast cancer

In the cell there is a large class of regulatory molecules referred to as microRNA. Many investigators regard microRNA Mir and Mir-155 as new potential prognostic markers and targets for goal-oriented therapy for breast cancer (BC) these days. MiR-21 and MiR-155 have been found to regulate the metas...

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Main Authors: M. A. Taipov, Z. N. Nikiphorova, K. P. Laktionov, N. E. Levchenko, V. E. Shevchenko
Format: Article
Language:Russian
Published: ABV-press 2014-07-01
Series:Опухоли женской репродуктивной системы
Subjects:
Online Access:https://ojrs.abvpress.ru/ojrs/article/view/49
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author M. A. Taipov
Z. N. Nikiphorova
K. P. Laktionov
N. E. Levchenko
V. E. Shevchenko
author_facet M. A. Taipov
Z. N. Nikiphorova
K. P. Laktionov
N. E. Levchenko
V. E. Shevchenko
author_sort M. A. Taipov
collection DOAJ
description In the cell there is a large class of regulatory molecules referred to as microRNA. Many investigators regard microRNA Mir and Mir-155 as new potential prognostic markers and targets for goal-oriented therapy for breast cancer (BC) these days. MiR-21 and MiR-155 have been found to regulate the metastatic potential of tumor cells and to be differentially expressed in the BC cells. Our review deals with the theoretical prerequisites for and practical results of studying MiR-21 and MiR-155 as potential molecular markers for BC.
format Article
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institution Kabale University
issn 1994-4098
1999-8627
language Russian
publishDate 2014-07-01
publisher ABV-press
record_format Article
series Опухоли женской репродуктивной системы
spelling doaj-art-510fa0c0f5eb4e5897cc8b70f7b2a3c42025-08-20T03:38:25ZrusABV-pressОпухоли женской репродуктивной системы1994-40981999-86272014-07-0103-461110.17650/1994-4098-2013-0-3-4-6-1164MicroRNA MiR-21 and MiR-155 are new markers for breast cancerM. A. Taipov0Z. N. Nikiphorova1K. P. Laktionov2N. E. Levchenko3V. E. Shevchenko4N.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, MoscowN.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, MoscowN.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, MoscowN.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, MoscowN.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, MoscowIn the cell there is a large class of regulatory molecules referred to as microRNA. Many investigators regard microRNA Mir and Mir-155 as new potential prognostic markers and targets for goal-oriented therapy for breast cancer (BC) these days. MiR-21 and MiR-155 have been found to regulate the metastatic potential of tumor cells and to be differentially expressed in the BC cells. Our review deals with the theoretical prerequisites for and practical results of studying MiR-21 and MiR-155 as potential molecular markers for BC.https://ojrs.abvpress.ru/ojrs/article/view/49breast cancermicrornamir-21mir-155cox-2tgf-1/smad signaling pathwaymarkerstargets for goal-oriented therapy
spellingShingle M. A. Taipov
Z. N. Nikiphorova
K. P. Laktionov
N. E. Levchenko
V. E. Shevchenko
MicroRNA MiR-21 and MiR-155 are new markers for breast cancer
Опухоли женской репродуктивной системы
breast cancer
microrna
mir-21
mir-155
cox-2
tgf-1/smad signaling pathway
markers
targets for goal-oriented therapy
title MicroRNA MiR-21 and MiR-155 are new markers for breast cancer
title_full MicroRNA MiR-21 and MiR-155 are new markers for breast cancer
title_fullStr MicroRNA MiR-21 and MiR-155 are new markers for breast cancer
title_full_unstemmed MicroRNA MiR-21 and MiR-155 are new markers for breast cancer
title_short MicroRNA MiR-21 and MiR-155 are new markers for breast cancer
title_sort microrna mir 21 and mir 155 are new markers for breast cancer
topic breast cancer
microrna
mir-21
mir-155
cox-2
tgf-1/smad signaling pathway
markers
targets for goal-oriented therapy
url https://ojrs.abvpress.ru/ojrs/article/view/49
work_keys_str_mv AT mataipov micrornamir21andmir155arenewmarkersforbreastcancer
AT znnikiphorova micrornamir21andmir155arenewmarkersforbreastcancer
AT kplaktionov micrornamir21andmir155arenewmarkersforbreastcancer
AT nelevchenko micrornamir21andmir155arenewmarkersforbreastcancer
AT veshevchenko micrornamir21andmir155arenewmarkersforbreastcancer