Matching Diabetes and Alcoholism: Oxidative Stress, Inflammation, and Neurogenesis Are Commonly Involved
Diabetes and alcohol misuse are two of the major challenges in health systems worldwide. These two diseases finally affect several organs and systems including the central nervous system. Hippocampus is one of the most relevant structures due to neurogenesis and memory-related processing among other...
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| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2015-01-01
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| Series: | Mediators of Inflammation |
| Online Access: | http://dx.doi.org/10.1155/2015/624287 |
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| author | Jorge M. Barcia Miguel Flores-Bellver Maria Muriach Javier Sancho-Pelluz Daniel Lopez-Malo Alba C. Urdaneta Natalia Martinez-Gil Sandra Atienzar-Aroca Francisco J. Romero |
| author_facet | Jorge M. Barcia Miguel Flores-Bellver Maria Muriach Javier Sancho-Pelluz Daniel Lopez-Malo Alba C. Urdaneta Natalia Martinez-Gil Sandra Atienzar-Aroca Francisco J. Romero |
| author_sort | Jorge M. Barcia |
| collection | DOAJ |
| description | Diabetes and alcohol misuse are two of the major challenges in health systems worldwide. These two diseases finally affect several organs and systems including the central nervous system. Hippocampus is one of the most relevant structures due to neurogenesis and memory-related processing among other functions. The present review focuses on the common profile of diabetes and ethanol exposure in terms of oxidative stress and proinflammatory and prosurvival recruiting transcription factors affecting hippocampal neurogenesis. Some aspects around antioxidant strategies are also included. As a global conclusion, the present review points out some common hits on both diseases giving support to the relations between alcohol intake and diabetes. |
| format | Article |
| id | doaj-art-510e893eb6d845d4ae9573b70a09e273 |
| institution | Kabale University |
| issn | 0962-9351 1466-1861 |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Mediators of Inflammation |
| spelling | doaj-art-510e893eb6d845d4ae9573b70a09e2732025-08-20T03:36:17ZengWileyMediators of Inflammation0962-93511466-18612015-01-01201510.1155/2015/624287624287Matching Diabetes and Alcoholism: Oxidative Stress, Inflammation, and Neurogenesis Are Commonly InvolvedJorge M. Barcia0Miguel Flores-Bellver1Maria Muriach2Javier Sancho-Pelluz3Daniel Lopez-Malo4Alba C. Urdaneta5Natalia Martinez-Gil6Sandra Atienzar-Aroca7Francisco J. Romero8Facultad de Medicina y Odontología, Universidad Católica de Valencia “San Vicente Mártir”, C/Quevedo 2, 46001 Valencia, SpainFacultad de Medicina y Odontología, Universidad Católica de Valencia “San Vicente Mártir”, C/Quevedo 2, 46001 Valencia, SpainUnidad Predepartamental de Medicina, Universitat Jaume I, 12071 Castellón de la Plana, SpainFacultad de Medicina y Odontología, Universidad Católica de Valencia “San Vicente Mártir”, C/Quevedo 2, 46001 Valencia, SpainFacultad de Medicina y Odontología, Universidad Católica de Valencia “San Vicente Mártir”, C/Quevedo 2, 46001 Valencia, SpainFacultad de Medicina y Odontología, Universidad Católica de Valencia “San Vicente Mártir”, C/Quevedo 2, 46001 Valencia, SpainFacultad de Medicina y Odontología, Universidad Católica de Valencia “San Vicente Mártir”, C/Quevedo 2, 46001 Valencia, SpainFacultad de Medicina y Odontología, Universidad Católica de Valencia “San Vicente Mártir”, C/Quevedo 2, 46001 Valencia, SpainFacultad de Medicina y Odontología, Universidad Católica de Valencia “San Vicente Mártir”, C/Quevedo 2, 46001 Valencia, SpainDiabetes and alcohol misuse are two of the major challenges in health systems worldwide. These two diseases finally affect several organs and systems including the central nervous system. Hippocampus is one of the most relevant structures due to neurogenesis and memory-related processing among other functions. The present review focuses on the common profile of diabetes and ethanol exposure in terms of oxidative stress and proinflammatory and prosurvival recruiting transcription factors affecting hippocampal neurogenesis. Some aspects around antioxidant strategies are also included. As a global conclusion, the present review points out some common hits on both diseases giving support to the relations between alcohol intake and diabetes.http://dx.doi.org/10.1155/2015/624287 |
| spellingShingle | Jorge M. Barcia Miguel Flores-Bellver Maria Muriach Javier Sancho-Pelluz Daniel Lopez-Malo Alba C. Urdaneta Natalia Martinez-Gil Sandra Atienzar-Aroca Francisco J. Romero Matching Diabetes and Alcoholism: Oxidative Stress, Inflammation, and Neurogenesis Are Commonly Involved Mediators of Inflammation |
| title | Matching Diabetes and Alcoholism: Oxidative Stress, Inflammation, and Neurogenesis Are Commonly Involved |
| title_full | Matching Diabetes and Alcoholism: Oxidative Stress, Inflammation, and Neurogenesis Are Commonly Involved |
| title_fullStr | Matching Diabetes and Alcoholism: Oxidative Stress, Inflammation, and Neurogenesis Are Commonly Involved |
| title_full_unstemmed | Matching Diabetes and Alcoholism: Oxidative Stress, Inflammation, and Neurogenesis Are Commonly Involved |
| title_short | Matching Diabetes and Alcoholism: Oxidative Stress, Inflammation, and Neurogenesis Are Commonly Involved |
| title_sort | matching diabetes and alcoholism oxidative stress inflammation and neurogenesis are commonly involved |
| url | http://dx.doi.org/10.1155/2015/624287 |
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