Population shift in antibody immunity following the emergence of a SARS-CoV-2 variant of concern

Population shift in antibody immunity following the emergence of a SARS-CoV-2 variant of concern

Abstract Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) variants of concern (VOCs) exhibit escape from pre-existing immunity and elicit variant-specific immune responses. In South Africa, the second wave of SARS-CoV-2 infections was driven by the Beta VOC, which coincided with the coun...

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Main Authors: Jinal N. Bhiman, Vimbai Sharon Madzorera, Qiniso Mkhize, Cathrine Scheepers, Tandile Hermanus, Frances Ayres, Zanele Makhado, Thandeka Moyo-Gwete, Carol Crowther, Beverley Singh, Mirriam Fortuin, Edmore Marinda, Sean Jooste, Khangelani Zuma, Nompumelelo Zungu, Lynn Morris, Adrian Puren, Leickness Simbayi, Sizulu Moyo, Penny L. Moore
Format: Article
Language:English
Published: Nature Portfolio 2025-02-01
Series:Scientific Reports
Subjects:
SARS-CoV-2
South Africa
Neutralizing antibodies
Antibody immunity
Population shift
Beta variant
Online Access:https://doi.org/10.1038/s41598-025-89940-y
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