Real-time visualization of HIV-1 GAG trafficking in infected macrophages.

Real-time visualization of HIV-1 GAG trafficking in infected macrophages.

HIV-1 particle production is driven by the Gag precursor protein Pr55(Gag). Despite significant progress in defining both the viral and cellular determinants of HIV-1 assembly and release, the trafficking pathway used by Gag to reach its site of assembly in the infected cell remains to be elucidated...

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Bibliographic Details
Main Authors: Karine Gousset, Sherimay D Ablan, Lori V Coren, Akira Ono, Ferri Soheilian, Kunio Nagashima, David E Ott, Eric O Freed
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-03-01
Series:PLoS Pathogens
Online Access:https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1000015&type=printable
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