Characterization of the Mitochondrial Genome of the Vietnamese Central Highland Wild Boar (<i>Sus scrofa</i>)

Hybridization between domestic pigs and wild boars of unknown origins has disrupted the precious gene pool of Vietnamese wild boar (<i>Sus scrofa</i>) populations in the Central Highlands. However, the genetic background of Vietnamese wild boars remains largely unknown. This study descri...

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Main Authors: Minh Thi Tran, Anh Le Hong Vo, Chi Nguyen Quynh Ho, Manh Quang Vu, Quan Minh To, Mai Thi Phuong Nguyen, Loan Thi Tung Dang, Nhan Lu Chinh Phan, Chung Chinh Doan, Huy Nghia Quang Hoang, Cuong Phan Minh Le, Son Nghia Hoang, Han Thai Minh Nguyen, Long Thanh Le
Format: Article
Language:English
Published: MDPI AG 2025-07-01
Series:Animals
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Online Access:https://www.mdpi.com/2076-2615/15/14/2029
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author Minh Thi Tran
Anh Le Hong Vo
Chi Nguyen Quynh Ho
Manh Quang Vu
Quan Minh To
Mai Thi Phuong Nguyen
Loan Thi Tung Dang
Nhan Lu Chinh Phan
Chung Chinh Doan
Huy Nghia Quang Hoang
Cuong Phan Minh Le
Son Nghia Hoang
Han Thai Minh Nguyen
Long Thanh Le
author_facet Minh Thi Tran
Anh Le Hong Vo
Chi Nguyen Quynh Ho
Manh Quang Vu
Quan Minh To
Mai Thi Phuong Nguyen
Loan Thi Tung Dang
Nhan Lu Chinh Phan
Chung Chinh Doan
Huy Nghia Quang Hoang
Cuong Phan Minh Le
Son Nghia Hoang
Han Thai Minh Nguyen
Long Thanh Le
author_sort Minh Thi Tran
collection DOAJ
description Hybridization between domestic pigs and wild boars of unknown origins has disrupted the precious gene pool of Vietnamese wild boar (<i>Sus scrofa</i>) populations in the Central Highlands. However, the genetic background of Vietnamese wild boars remains largely unknown. This study describes the complete mitochondrial genome of the Vietnamese Central Highland wild boar, a circular molecule comprising 16,581 base pairs (bp). The mitogenome contains 37 genes, which encode for 2 ribosomal RNAs, 22 transfer RNAs, and 13 mitochondrial proteins. It has a conserved gene order, gene orientation, and similar nucleotide composition indexes to other boars and pig breeds across the world. Notably, 232 nucleotide substitutions were detected when comparing this genome with 19 previously described <i>Sus scrofa</i> genomes. Partial <i>cytochrome b</i> gene analysis revealed the distribution of Asian haplotypes in the Vietnamese Central Highland <i>Sus scrofa</i>. A phylogenetic tree constructed from 32 <i>Sus scrofa</i>’s whole mitogenome sequences demonstrated the close relationship between Vietnamese wild boars and domestic pig breeds. The study provides additional insights into the genetics of Vietnamese wild boars, paving the way for future research in conservation, evolution, and breeding of Vietnamese wild boar populations.
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spelling doaj-art-510966beac6d4d8a9949fb2ace14e25a2025-08-20T03:13:44ZengMDPI AGAnimals2076-26152025-07-011514202910.3390/ani15142029Characterization of the Mitochondrial Genome of the Vietnamese Central Highland Wild Boar (<i>Sus scrofa</i>)Minh Thi Tran0Anh Le Hong Vo1Chi Nguyen Quynh Ho2Manh Quang Vu3Quan Minh To4Mai Thi Phuong Nguyen5Loan Thi Tung Dang6Nhan Lu Chinh Phan7Chung Chinh Doan8Huy Nghia Quang Hoang9Cuong Phan Minh Le10Son Nghia Hoang11Han Thai Minh Nguyen12Long Thanh Le13Faculty of Applied Technology, Van Lang University, 69/68 Dang Thuy Tram Street, Binh Loi Trung Ward, Ho Chi Minh City 70000, VietnamFaculty of Biology and Biotechnology, University of Science, Vietnam National University, Ho Chi Minh City 70000, VietnamInstitute of Life Sciences, Vietnam Academy of Science and Technology, Ho Chi Minh City 70000, VietnamInstitute of Life Science and Application, Hoa Binh University (HBU), Nam Tu Liem, Hanoi 100000, VietnamFaculty of Biology and Biotechnology, University of Science, Vietnam National University, Ho Chi Minh City 70000, VietnamInstitute of Life Sciences, Vietnam Academy of Science and Technology, Ho Chi Minh City 70000, VietnamFaculty of Biology and Biotechnology, University of Science, Vietnam National University, Ho Chi Minh City 70000, VietnamInstitute of Life Sciences, Vietnam Academy of Science and Technology, Ho Chi Minh City 70000, VietnamInstitute of Life Sciences, Vietnam Academy of Science and Technology, Ho Chi Minh City 70000, VietnamInstitute of Life Sciences, Vietnam Academy of Science and Technology, Ho Chi Minh City 70000, VietnamInstitute of Life Sciences, Vietnam Academy of Science and Technology, Ho Chi Minh City 70000, VietnamInstitute of Life Sciences, Vietnam Academy of Science and Technology, Ho Chi Minh City 70000, VietnamInstitute of Life Sciences, Vietnam Academy of Science and Technology, Ho Chi Minh City 70000, VietnamInstitute of Life Sciences, Vietnam Academy of Science and Technology, Ho Chi Minh City 70000, VietnamHybridization between domestic pigs and wild boars of unknown origins has disrupted the precious gene pool of Vietnamese wild boar (<i>Sus scrofa</i>) populations in the Central Highlands. However, the genetic background of Vietnamese wild boars remains largely unknown. This study describes the complete mitochondrial genome of the Vietnamese Central Highland wild boar, a circular molecule comprising 16,581 base pairs (bp). The mitogenome contains 37 genes, which encode for 2 ribosomal RNAs, 22 transfer RNAs, and 13 mitochondrial proteins. It has a conserved gene order, gene orientation, and similar nucleotide composition indexes to other boars and pig breeds across the world. Notably, 232 nucleotide substitutions were detected when comparing this genome with 19 previously described <i>Sus scrofa</i> genomes. Partial <i>cytochrome b</i> gene analysis revealed the distribution of Asian haplotypes in the Vietnamese Central Highland <i>Sus scrofa</i>. A phylogenetic tree constructed from 32 <i>Sus scrofa</i>’s whole mitogenome sequences demonstrated the close relationship between Vietnamese wild boars and domestic pig breeds. The study provides additional insights into the genetics of Vietnamese wild boars, paving the way for future research in conservation, evolution, and breeding of Vietnamese wild boar populations.https://www.mdpi.com/2076-2615/15/14/2029Vietnamese pigcomplete mitogenomephylogenetic
spellingShingle Minh Thi Tran
Anh Le Hong Vo
Chi Nguyen Quynh Ho
Manh Quang Vu
Quan Minh To
Mai Thi Phuong Nguyen
Loan Thi Tung Dang
Nhan Lu Chinh Phan
Chung Chinh Doan
Huy Nghia Quang Hoang
Cuong Phan Minh Le
Son Nghia Hoang
Han Thai Minh Nguyen
Long Thanh Le
Characterization of the Mitochondrial Genome of the Vietnamese Central Highland Wild Boar (<i>Sus scrofa</i>)
Animals
Vietnamese pig
complete mitogenome
phylogenetic
title Characterization of the Mitochondrial Genome of the Vietnamese Central Highland Wild Boar (<i>Sus scrofa</i>)
title_full Characterization of the Mitochondrial Genome of the Vietnamese Central Highland Wild Boar (<i>Sus scrofa</i>)
title_fullStr Characterization of the Mitochondrial Genome of the Vietnamese Central Highland Wild Boar (<i>Sus scrofa</i>)
title_full_unstemmed Characterization of the Mitochondrial Genome of the Vietnamese Central Highland Wild Boar (<i>Sus scrofa</i>)
title_short Characterization of the Mitochondrial Genome of the Vietnamese Central Highland Wild Boar (<i>Sus scrofa</i>)
title_sort characterization of the mitochondrial genome of the vietnamese central highland wild boar i sus scrofa i
topic Vietnamese pig
complete mitogenome
phylogenetic
url https://www.mdpi.com/2076-2615/15/14/2029
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