Contrast-enhanced ultrasound (CEUS) for the diagnosis of axillary lymph nodes in breast cancer: A systematic review and meta-analysis
Objective: To evaluate the accuracy of contrast-enhanced ultrasound (CEUS) for the diagnosis of axillary lymph nodes in breast cancer. Methods: PubMed, EMBASE, The Cochrane Library, Chinese Biomedical Literature Database, the full database of China, Chinese National Knowledge Infrastructure, and Wan...
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Elsevier
2024-12-01
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| Series: | WFUMB Ultrasound Open |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2949668324000223 |
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| author | Le Chong Luhua Xia Xiulan Wu Hongyu Li Zhiying Jia |
| author_facet | Le Chong Luhua Xia Xiulan Wu Hongyu Li Zhiying Jia |
| author_sort | Le Chong |
| collection | DOAJ |
| description | Objective: To evaluate the accuracy of contrast-enhanced ultrasound (CEUS) for the diagnosis of axillary lymph nodes in breast cancer. Methods: PubMed, EMBASE, The Cochrane Library, Chinese Biomedical Literature Database, the full database of China, Chinese National Knowledge Infrastructure, and Wanfang database databases were utilized. Perspective studies regarding CEUS diagnosis of axillary lymph nodes in breast cancer were included. QUADAS-2 was used to estimate the research quality by two reviewers independently. Metadisc1.4 software and Stata 14.0 were used to examine data from the included studies. The diagnostic value of CEUS was assessed by aspects such as summary sensitivity, specificity, receiver operating characteristic (SROC). Results: Fourteen studies were included and 1127 patients were included. A meta-analysis showed that the summary sensitivity of CEUS was 0.85 (95 % CI 0.82–0.87), the specificity was 0.86 (95 % CI 0.82–0.89), the diagnostic odds ratio was 31.15 (95 % CI 17.16–56.52) and the SROC was 0.9186. Conclusions: CEUS diagnosis of axillary lymph nodes in breast cancer has high sensitivity and specificity and it is the preferred method to diagnose axillary lymph nodes in breast cancer in clinical practice. |
| format | Article |
| id | doaj-art-50e7dc5fe9f049ad8ab2a5acde723afc |
| institution | OA Journals |
| issn | 2949-6683 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | WFUMB Ultrasound Open |
| spelling | doaj-art-50e7dc5fe9f049ad8ab2a5acde723afc2025-08-20T02:38:46ZengElsevierWFUMB Ultrasound Open2949-66832024-12-012210005410.1016/j.wfumbo.2024.100054Contrast-enhanced ultrasound (CEUS) for the diagnosis of axillary lymph nodes in breast cancer: A systematic review and meta-analysisLe Chong0Luhua Xia1Xiulan Wu2Hongyu Li3Zhiying Jia4Department of Ultrasonography, The Affiliated Cancer Hospital of Xinjiang Medical University, Urumqi, Xinjiang, 830011, ChinaDepartment of Nuclear Medicine, The Affiliated Cancer Hospital of Xinjiang Medical University, Urumqi, Xinjiang, 830011, ChinaDepartment of Ultrasonography, The Affiliated Cancer Hospital of Xinjiang Medical University, Urumqi, Xinjiang, 830011, ChinaDepartment of Breast Medicine, The Affiliated Cancer Hospital of Xinjiang Medical University, Urumqi, Xinjiang, 830011, ChinaDepartment of Ultrasonography, The Affiliated Cancer Hospital of Xinjiang Medical University, Urumqi, Xinjiang, 830011, China; Corresponding author.Objective: To evaluate the accuracy of contrast-enhanced ultrasound (CEUS) for the diagnosis of axillary lymph nodes in breast cancer. Methods: PubMed, EMBASE, The Cochrane Library, Chinese Biomedical Literature Database, the full database of China, Chinese National Knowledge Infrastructure, and Wanfang database databases were utilized. Perspective studies regarding CEUS diagnosis of axillary lymph nodes in breast cancer were included. QUADAS-2 was used to estimate the research quality by two reviewers independently. Metadisc1.4 software and Stata 14.0 were used to examine data from the included studies. The diagnostic value of CEUS was assessed by aspects such as summary sensitivity, specificity, receiver operating characteristic (SROC). Results: Fourteen studies were included and 1127 patients were included. A meta-analysis showed that the summary sensitivity of CEUS was 0.85 (95 % CI 0.82–0.87), the specificity was 0.86 (95 % CI 0.82–0.89), the diagnostic odds ratio was 31.15 (95 % CI 17.16–56.52) and the SROC was 0.9186. Conclusions: CEUS diagnosis of axillary lymph nodes in breast cancer has high sensitivity and specificity and it is the preferred method to diagnose axillary lymph nodes in breast cancer in clinical practice.http://www.sciencedirect.com/science/article/pii/S2949668324000223Contrast-enhanced ultrasound (CEUS)Diagnosisaxillary lymph nodesBreast cancer |
| spellingShingle | Le Chong Luhua Xia Xiulan Wu Hongyu Li Zhiying Jia Contrast-enhanced ultrasound (CEUS) for the diagnosis of axillary lymph nodes in breast cancer: A systematic review and meta-analysis WFUMB Ultrasound Open Contrast-enhanced ultrasound (CEUS) Diagnosis axillary lymph nodes Breast cancer |
| title | Contrast-enhanced ultrasound (CEUS) for the diagnosis of axillary lymph nodes in breast cancer: A systematic review and meta-analysis |
| title_full | Contrast-enhanced ultrasound (CEUS) for the diagnosis of axillary lymph nodes in breast cancer: A systematic review and meta-analysis |
| title_fullStr | Contrast-enhanced ultrasound (CEUS) for the diagnosis of axillary lymph nodes in breast cancer: A systematic review and meta-analysis |
| title_full_unstemmed | Contrast-enhanced ultrasound (CEUS) for the diagnosis of axillary lymph nodes in breast cancer: A systematic review and meta-analysis |
| title_short | Contrast-enhanced ultrasound (CEUS) for the diagnosis of axillary lymph nodes in breast cancer: A systematic review and meta-analysis |
| title_sort | contrast enhanced ultrasound ceus for the diagnosis of axillary lymph nodes in breast cancer a systematic review and meta analysis |
| topic | Contrast-enhanced ultrasound (CEUS) Diagnosis axillary lymph nodes Breast cancer |
| url | http://www.sciencedirect.com/science/article/pii/S2949668324000223 |
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