Disinfection of indoor air for the inactivation of SARS-CoV-2: a review of the effectiveness of UV-C technology and gaps in research

Coronavirus disease (COVID-19) is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). In indoor environments, a structured strategy is needed to reduce the risk of infection. In addition to maintaining proper ventilation and wearing face masks, the development of effective techno...

Full description

Saved in:
Bibliographic Details
Main Authors: Elena Cristina Rada, Chiara Vignali, Stefano Bellazzi, Marco Carnevale Miino, Alessandro Abbà, Márta Szabó, Vincenzo Torretta, Maria Cristina Collivignarelli
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Built Environment
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fbuil.2024.1523055/full
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1850031612688859136
author Elena Cristina Rada
Chiara Vignali
Stefano Bellazzi
Marco Carnevale Miino
Alessandro Abbà
Márta Szabó
Vincenzo Torretta
Maria Cristina Collivignarelli
Maria Cristina Collivignarelli
author_facet Elena Cristina Rada
Chiara Vignali
Stefano Bellazzi
Marco Carnevale Miino
Alessandro Abbà
Márta Szabó
Vincenzo Torretta
Maria Cristina Collivignarelli
Maria Cristina Collivignarelli
author_sort Elena Cristina Rada
collection DOAJ
description Coronavirus disease (COVID-19) is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). In indoor environments, a structured strategy is needed to reduce the risk of infection. In addition to maintaining proper ventilation and wearing face masks, the development of effective technologies for limiting the transmission of SARS-CoV-2 through infectious respiratory particles (IRPs) has been studied. UV-C devices have already proved effective against other types of microorganisms and have also been investigated for their potential in inactivating SARS-CoV-2. This work aims to review and discuss these findings while also presenting recommendations for future research. Based on the available data, UV-C proved to be effective in the inactivation of airborne SARS-CoV-2 or its surrogates. The main gaps in this research have also been highlighted, and some outlooks for future studies have been suggested. In some studies, the use of surrogates with higher susceptibility to UV-C than airborne SARS-CoV-2 or the consideration of total bacterial counts alone may have led to misleading results. The question “how much variables affect the inactivation rate of airborne SARS-CoV-2 by UV-C in indoor environments?” is still unsolved, considering that the number of studies on the inactivation of this virus in real indoor environments is quite limited. The outcomes of this study can be useful for the scientific community, the technical stakeholders (e.g., managers in the healthcare and transport sectors), and the common people, providing important information about the performance of these technologies to improve the quality of air in indoor environments.
format Article
id doaj-art-50df3c9b8e7147f0a22f2d5f702f2407
institution DOAJ
issn 2297-3362
language English
publishDate 2025-01-01
publisher Frontiers Media S.A.
record_format Article
series Frontiers in Built Environment
spelling doaj-art-50df3c9b8e7147f0a22f2d5f702f24072025-08-20T02:58:55ZengFrontiers Media S.A.Frontiers in Built Environment2297-33622025-01-011010.3389/fbuil.2024.15230551523055Disinfection of indoor air for the inactivation of SARS-CoV-2: a review of the effectiveness of UV-C technology and gaps in researchElena Cristina Rada0Chiara Vignali1Stefano Bellazzi2Marco Carnevale Miino3Alessandro Abbà4Márta Szabó5Vincenzo Torretta6Maria Cristina Collivignarelli7Maria Cristina Collivignarelli8Department of Theoretical and Applied Sciences, University of Insubria, Varese, ItalyDepartment of Civil Engineering and Architecture, University of Pavia, Pavia, ItalyDepartment of Civil Engineering and Architecture, University of Pavia, Pavia, ItalyDepartment of Theoretical and Applied Sciences, University of Insubria, Varese, ItalyDepartment of Civil, Environmental, Architectural Engineering and Mathematics, University of Brescia, Brescia, ItalyDepartment of Building Engineering and Energetics, Institute of Technology, MATE, Gödöllő, HungaryDepartment of Theoretical and Applied Sciences, University of Insubria, Varese, ItalyDepartment of Civil Engineering and Architecture, University of Pavia, Pavia, ItalyInterdepartmental Centre for Water Research, University of Pavia, Pavia, ItalyCoronavirus disease (COVID-19) is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). In indoor environments, a structured strategy is needed to reduce the risk of infection. In addition to maintaining proper ventilation and wearing face masks, the development of effective technologies for limiting the transmission of SARS-CoV-2 through infectious respiratory particles (IRPs) has been studied. UV-C devices have already proved effective against other types of microorganisms and have also been investigated for their potential in inactivating SARS-CoV-2. This work aims to review and discuss these findings while also presenting recommendations for future research. Based on the available data, UV-C proved to be effective in the inactivation of airborne SARS-CoV-2 or its surrogates. The main gaps in this research have also been highlighted, and some outlooks for future studies have been suggested. In some studies, the use of surrogates with higher susceptibility to UV-C than airborne SARS-CoV-2 or the consideration of total bacterial counts alone may have led to misleading results. The question “how much variables affect the inactivation rate of airborne SARS-CoV-2 by UV-C in indoor environments?” is still unsolved, considering that the number of studies on the inactivation of this virus in real indoor environments is quite limited. The outcomes of this study can be useful for the scientific community, the technical stakeholders (e.g., managers in the healthcare and transport sectors), and the common people, providing important information about the performance of these technologies to improve the quality of air in indoor environments.https://www.frontiersin.org/articles/10.3389/fbuil.2024.1523055/fullCOVID-19pandemicindoor pollutantsairborne viruspathogensUV disinfection
spellingShingle Elena Cristina Rada
Chiara Vignali
Stefano Bellazzi
Marco Carnevale Miino
Alessandro Abbà
Márta Szabó
Vincenzo Torretta
Maria Cristina Collivignarelli
Maria Cristina Collivignarelli
Disinfection of indoor air for the inactivation of SARS-CoV-2: a review of the effectiveness of UV-C technology and gaps in research
Frontiers in Built Environment
COVID-19
pandemic
indoor pollutants
airborne virus
pathogens
UV disinfection
title Disinfection of indoor air for the inactivation of SARS-CoV-2: a review of the effectiveness of UV-C technology and gaps in research
title_full Disinfection of indoor air for the inactivation of SARS-CoV-2: a review of the effectiveness of UV-C technology and gaps in research
title_fullStr Disinfection of indoor air for the inactivation of SARS-CoV-2: a review of the effectiveness of UV-C technology and gaps in research
title_full_unstemmed Disinfection of indoor air for the inactivation of SARS-CoV-2: a review of the effectiveness of UV-C technology and gaps in research
title_short Disinfection of indoor air for the inactivation of SARS-CoV-2: a review of the effectiveness of UV-C technology and gaps in research
title_sort disinfection of indoor air for the inactivation of sars cov 2 a review of the effectiveness of uv c technology and gaps in research
topic COVID-19
pandemic
indoor pollutants
airborne virus
pathogens
UV disinfection
url https://www.frontiersin.org/articles/10.3389/fbuil.2024.1523055/full
work_keys_str_mv AT elenacristinarada disinfectionofindoorairfortheinactivationofsarscov2areviewoftheeffectivenessofuvctechnologyandgapsinresearch
AT chiaravignali disinfectionofindoorairfortheinactivationofsarscov2areviewoftheeffectivenessofuvctechnologyandgapsinresearch
AT stefanobellazzi disinfectionofindoorairfortheinactivationofsarscov2areviewoftheeffectivenessofuvctechnologyandgapsinresearch
AT marcocarnevalemiino disinfectionofindoorairfortheinactivationofsarscov2areviewoftheeffectivenessofuvctechnologyandgapsinresearch
AT alessandroabba disinfectionofindoorairfortheinactivationofsarscov2areviewoftheeffectivenessofuvctechnologyandgapsinresearch
AT martaszabo disinfectionofindoorairfortheinactivationofsarscov2areviewoftheeffectivenessofuvctechnologyandgapsinresearch
AT vincenzotorretta disinfectionofindoorairfortheinactivationofsarscov2areviewoftheeffectivenessofuvctechnologyandgapsinresearch
AT mariacristinacollivignarelli disinfectionofindoorairfortheinactivationofsarscov2areviewoftheeffectivenessofuvctechnologyandgapsinresearch
AT mariacristinacollivignarelli disinfectionofindoorairfortheinactivationofsarscov2areviewoftheeffectivenessofuvctechnologyandgapsinresearch