Mechanisms of drug resistance in hepatocellular carcinoma

Mechanisms of drug resistance in hepatocellular carcinoma

Abstract Hepatocellular carcinoma (HCC) is the most prevalent form of primary liver cancer, associated with high morbidity and mortality worldwide. Despite advancements in diagnostic methods and systemic treatments, including tyrosine kinase inhibitors (TKIs) and immune checkpoint inhibitors (ICIs),...

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Bibliographic Details
Main Authors: Yongchun Zou, Xinliang Wan, Qichun Zhou, Gangxing Zhu, Shanshan Lin, Qing Tang, Xiaobing Yang, Sumei Wang
Format: Article
Language:English
Published: BMC 2025-05-01
Series:Biological Procedures Online
Subjects:
Hepatocellular carcinoma
Drug resistance
Targeted therapy
Immune checkpoint inhibitors
Tumor microenvironment
Online Access:https://doi.org/10.1186/s12575-025-00281-6
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