Polyamine Metabolism and Functions: Key Roles in Cellular Health and Disease
The polyamines putrescine, spermidine, and spermine are polycations ubiquitously present in cells, where they exert pleiotropic functions in cellular mechanisms like proliferation, protein synthesis (through the hypusination of the transcription factor EIF5a), redox balance, autophagy, and different...
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| Format: | Article |
| Language: | English |
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MDPI AG
2024-12-01
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| Series: | Biomolecules |
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| Online Access: | https://www.mdpi.com/2218-273X/14/12/1570 |
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| _version_ | 1846105561023643648 |
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| author | Marianna Nicoletta Rossi Manuela Cervelli |
| author_facet | Marianna Nicoletta Rossi Manuela Cervelli |
| author_sort | Marianna Nicoletta Rossi |
| collection | DOAJ |
| description | The polyamines putrescine, spermidine, and spermine are polycations ubiquitously present in cells, where they exert pleiotropic functions in cellular mechanisms like proliferation, protein synthesis (through the hypusination of the transcription factor EIF5a), redox balance, autophagy, and different forms of cell death [...] |
| format | Article |
| id | doaj-art-50d15d41979b4e438eaadc35a7d24829 |
| institution | Kabale University |
| issn | 2218-273X |
| language | English |
| publishDate | 2024-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Biomolecules |
| spelling | doaj-art-50d15d41979b4e438eaadc35a7d248292024-12-27T14:13:49ZengMDPI AGBiomolecules2218-273X2024-12-011412157010.3390/biom14121570Polyamine Metabolism and Functions: Key Roles in Cellular Health and DiseaseMarianna Nicoletta Rossi0Manuela Cervelli1Department of Sciences, University of Roma Tre, 00146 Rome, ItalyDepartment of Sciences, University of Roma Tre, 00146 Rome, ItalyThe polyamines putrescine, spermidine, and spermine are polycations ubiquitously present in cells, where they exert pleiotropic functions in cellular mechanisms like proliferation, protein synthesis (through the hypusination of the transcription factor EIF5a), redox balance, autophagy, and different forms of cell death [...]https://www.mdpi.com/2218-273X/14/12/1570n/a |
| spellingShingle | Marianna Nicoletta Rossi Manuela Cervelli Polyamine Metabolism and Functions: Key Roles in Cellular Health and Disease Biomolecules n/a |
| title | Polyamine Metabolism and Functions: Key Roles in Cellular Health and Disease |
| title_full | Polyamine Metabolism and Functions: Key Roles in Cellular Health and Disease |
| title_fullStr | Polyamine Metabolism and Functions: Key Roles in Cellular Health and Disease |
| title_full_unstemmed | Polyamine Metabolism and Functions: Key Roles in Cellular Health and Disease |
| title_short | Polyamine Metabolism and Functions: Key Roles in Cellular Health and Disease |
| title_sort | polyamine metabolism and functions key roles in cellular health and disease |
| topic | n/a |
| url | https://www.mdpi.com/2218-273X/14/12/1570 |
| work_keys_str_mv | AT mariannanicolettarossi polyaminemetabolismandfunctionskeyrolesincellularhealthanddisease AT manuelacervelli polyaminemetabolismandfunctionskeyrolesincellularhealthanddisease |