Association of critically short telomeres with brain and blood markers of ageing and Alzheimer’s disease in older adults

Association of critically short telomeres with brain and blood markers of ageing and Alzheimer’s disease in older adults

Abstract Background Accumulation of critically short telomeres (CST) is implicated in decreased tissular regenerative capacity and increased susceptibility to degenerative diseases such as Alzheimer’s disease (AD). Telomere shortening has also been associated with age-related brain changes. However,...

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Bibliographic Details
Main Authors: Asrar Lehodey, Perla Kaliman, Cassandre Palix, Robin de Florès, Edelweiss Touron, Anne-Laure Turpin, Séverine Fauvel, Florence Mézenge, Brigitte Landeau, Anne Chocat, Agathe Vrillon, Claire Paquet, Denis Vivien, Vincent de La Sayette, Gaël Chételat, Géraldine Poisnel, the Medit-Ageing Research Group
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Alzheimer’s Research & Therapy
Subjects:
Telomeres
Biomarkers
Neuroimaging
Ageing
Alzheimer’s disease
Online Access:https://doi.org/10.1186/s13195-024-01635-0
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