The impact of phthalates on asthma and chronic obstructive pulmonary disease: a comprehensive analysis based on network toxicology and molecular docking

The impact of phthalates on asthma and chronic obstructive pulmonary disease: a comprehensive analysis based on network toxicology and molecular docking

IntroductionPhthalates (PAEs) are widely used plasticizers in polyvinyl chloride (PVC) products since the 1930s, and recent research indicates a significant association between exposure to these substances and the development and progression of asthma and chronic obstructive pulmonary disease (COPD)...

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Main Authors: Ren Li, Bingqing Zheng, Yuqiong Zhang, Lu He, Chaomin Ren, Linlin Guan, Huan Yang, Jiayu Tian, Xingyi Chen, Dongxing Shi, Lifang Zhao, Zhihong Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-03-01
Series:Frontiers in Pharmacology
Subjects:
phthalates
asthma
COPD
network toxicology
molecular docking
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1566965/full
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