BRUGADA SYNDROME: FROM PRIMARY ELECTRIC HEART DISEASE TO MORPHOLOGICAL SUBSTRATE

Nowadays interest in channelopathies is growing, and developing diagnostic capabilities make Brugada syndrome much more actual problem than ever. Conception of «primary electric heart disease», which earlier was so popular, now couldn’t explain the absence of single genetic syndromes’ substrate, its...

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Main Authors: T. A. Pavlenko, O. V. Blagova
Format: Article
Language:Russian
Published: SINAPS LLC 2016-05-01
Series:Архивъ внутренней медицины
Subjects:
Online Access:https://www.medarhive.ru/jour/article/view/521
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author T. A. Pavlenko
O. V. Blagova
author_facet T. A. Pavlenko
O. V. Blagova
author_sort T. A. Pavlenko
collection DOAJ
description Nowadays interest in channelopathies is growing, and developing diagnostic capabilities make Brugada syndrome much more actual problem than ever. Conception of «primary electric heart disease», which earlier was so popular, now couldn’t explain the absence of single genetic syndromes’ substrate, its’ common combinations with another arrhythmias and the presence of Brugada phenocopy. Conjunction of Brugada syndrome with morphological changes in myocardium , especially myocarditis, is an area of special interest. Infl ammation associates with clinical manifestation of the syndrome, and this situation forces to think about channelopathies’ primacy and to look for another possible mechanisms of Brugada syndrome.
format Article
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series Архивъ внутренней медицины
spelling doaj-art-50aed04ecd484910bdbee5769262a7d82025-08-20T04:00:03ZrusSINAPS LLCАрхивъ внутренней медицины2226-67042411-65642016-05-0162616910.20514/2226-6704-2016-6-2-61-69512BRUGADA SYNDROME: FROM PRIMARY ELECTRIC HEART DISEASE TO MORPHOLOGICAL SUBSTRATET. A. Pavlenko0O. V. Blagova1First Moscow State Medical University named after I.M. SechenovFirst Moscow State Medical University named after I.M. SechenovNowadays interest in channelopathies is growing, and developing diagnostic capabilities make Brugada syndrome much more actual problem than ever. Conception of «primary electric heart disease», which earlier was so popular, now couldn’t explain the absence of single genetic syndromes’ substrate, its’ common combinations with another arrhythmias and the presence of Brugada phenocopy. Conjunction of Brugada syndrome with morphological changes in myocardium , especially myocarditis, is an area of special interest. Infl ammation associates with clinical manifestation of the syndrome, and this situation forces to think about channelopathies’ primacy and to look for another possible mechanisms of Brugada syndrome.https://www.medarhive.ru/jour/article/view/521brugada syndromemyocarditischannelopathiesphenocopyelectric remodelling
spellingShingle T. A. Pavlenko
O. V. Blagova
BRUGADA SYNDROME: FROM PRIMARY ELECTRIC HEART DISEASE TO MORPHOLOGICAL SUBSTRATE
Архивъ внутренней медицины
brugada syndrome
myocarditis
channelopathies
phenocopy
electric remodelling
title BRUGADA SYNDROME: FROM PRIMARY ELECTRIC HEART DISEASE TO MORPHOLOGICAL SUBSTRATE
title_full BRUGADA SYNDROME: FROM PRIMARY ELECTRIC HEART DISEASE TO MORPHOLOGICAL SUBSTRATE
title_fullStr BRUGADA SYNDROME: FROM PRIMARY ELECTRIC HEART DISEASE TO MORPHOLOGICAL SUBSTRATE
title_full_unstemmed BRUGADA SYNDROME: FROM PRIMARY ELECTRIC HEART DISEASE TO MORPHOLOGICAL SUBSTRATE
title_short BRUGADA SYNDROME: FROM PRIMARY ELECTRIC HEART DISEASE TO MORPHOLOGICAL SUBSTRATE
title_sort brugada syndrome from primary electric heart disease to morphological substrate
topic brugada syndrome
myocarditis
channelopathies
phenocopy
electric remodelling
url https://www.medarhive.ru/jour/article/view/521
work_keys_str_mv AT tapavlenko brugadasyndromefromprimaryelectricheartdiseasetomorphologicalsubstrate
AT ovblagova brugadasyndromefromprimaryelectricheartdiseasetomorphologicalsubstrate