Myocardial mitochondrial antiviral signaling protein promotes heart Ischemia-reperfusion injury via RIG-I signaling in mice

Myocardial mitochondrial antiviral signaling protein promotes heart Ischemia-reperfusion injury via RIG-I signaling in mice

Abstract Myocardial ischemia-reperfusion injury (MIRI) is a life-threatening complication of myocardial infarcts, with inner mitochondrial membrane protein dysfunction involved in MIRI-induced heart injury. The role of outer mitochondrial membrane protein mitochondrial antiviral signaling protein (M...

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Main Authors: Zhenyu Kang, Mengling Yang, Yue Liu, Yang Gui, Yalan Dong, Haifeng Zhou, Zili Zhang, Mingyue Li, Heng Fan, Zheng Li, Junjie Lu, Junyi Li, Rui Zhu, Chengyu Yin, Boyi Liu, Feng Jiang, Kun Huang, Alexey Sarapultsev, Fangfei Li, Ge Zhang, Ling Zhao, Yanyi Wang, Yunjia Ning, Xiang Cheng, Sarajo K. Mohanta, Changjun Yin, Shanshan Luo, Andreas J. R. Habenicht, Desheng Hu
Format: Article
Language:English
Published: Nature Portfolio 2025-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-60123-7
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