Bcl-xL Genetic Modification Enhanced the Therapeutic Efficacy of Mesenchymal Stem Cell Transplantation in the Treatment of Heart Infarction

Bcl-xL Genetic Modification Enhanced the Therapeutic Efficacy of Mesenchymal Stem Cell Transplantation in the Treatment of Heart Infarction

Objectives. Low survival rate of mesenchymal stem cells (MSCs) severely limited the therapeutic efficacy of cell therapy in the treatment of myocardial infarction (MI). Bcl-xL genetic modification might enhance MSC survival after transplantation. Methods. Adult rat bone marrow MSCs were modified wit...

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Bibliographic Details
Main Authors:	Xiaodong Xue, Yu Liu, Jian Zhang, Tao Liu, Zhonglu Yang, Huishan Wang
Format:	Article
Language:	English
Published:	Wiley 2015-01-01
Series:	Stem Cells International
Online Access:	http://dx.doi.org/10.1155/2015/176409
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