Amyloid PET ordering practices in a memory disorders clinic

Abstract Introduction This study assessed the ordering of amyloid positron emission tomography (PET) scans in a Veterans Affairs (VA) memory disorders clinic as part of routine clinical care, with possible implications for the extent to which ordering may occur outside of the VA in the future if cov...

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Main Authors: Katherine W. Turk, Ana Vives‐Rodriguez, Kylie A. Schiloski, Anna Marin, Ryan Wang, Prabhjyot Singh, Gabor P. Hajos, Rachel Powsner, Renée DeCaro, Andrew E. Budson
Format: Article
Language:English
Published: Wiley 2022-01-01
Series:Alzheimer’s & Dementia: Translational Research & Clinical Interventions
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Online Access:https://doi.org/10.1002/trc2.12333
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author Katherine W. Turk
Ana Vives‐Rodriguez
Kylie A. Schiloski
Anna Marin
Ryan Wang
Prabhjyot Singh
Gabor P. Hajos
Rachel Powsner
Renée DeCaro
Andrew E. Budson
author_facet Katherine W. Turk
Ana Vives‐Rodriguez
Kylie A. Schiloski
Anna Marin
Ryan Wang
Prabhjyot Singh
Gabor P. Hajos
Rachel Powsner
Renée DeCaro
Andrew E. Budson
author_sort Katherine W. Turk
collection DOAJ
description Abstract Introduction This study assessed the ordering of amyloid positron emission tomography (PET) scans in a Veterans Affairs (VA) memory disorders clinic as part of routine clinical care, with possible implications for the extent to which ordering may occur outside of the VA in the future if covered by insurance. Methods Clinical features predictive of ordering amyloid PET scans were retrospectively assessed; the percentage of patients who met appropriate use criteria were evaluated. Results Among 565 veterans, 34.9% of received an amyloid PET scan and 98.0% of these were consistent with appropriate use criteria. Patients with a PET were younger and more likely to have an initial diagnosis of Alzheimer's disease (AD). Of patients without an amyloid PET scan ordered, 64.4% would have met appropriate use criteria for amyloid PET. Discussion The majority of scans ordered were consistent with appropriate use criteria and more patients were eligible than received a scan. The current study's findings that approximately one‐third of patients in a memory disorders clinic received an amyloid PET scan has implications for memory disorders clinics inside and outside of the US Veterans Health Administration.
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series Alzheimer’s & Dementia: Translational Research & Clinical Interventions
spelling doaj-art-5094f22963de426b9b5b7e50ec6d53362025-08-20T02:50:40ZengWileyAlzheimer’s & Dementia: Translational Research & Clinical Interventions2352-87372022-01-0181n/an/a10.1002/trc2.12333Amyloid PET ordering practices in a memory disorders clinicKatherine W. Turk0Ana Vives‐Rodriguez1Kylie A. Schiloski2Anna Marin3Ryan Wang4Prabhjyot Singh5Gabor P. Hajos6Rachel Powsner7Renée DeCaro8Andrew E. Budson9Center for Translational Cognitive Neuroscience VA Boston Healthcare System Boston Massachusetts USACenter for Translational Cognitive Neuroscience VA Boston Healthcare System Boston Massachusetts USACenter for Translational Cognitive Neuroscience VA Boston Healthcare System Boston Massachusetts USACenter for Translational Cognitive Neuroscience VA Boston Healthcare System Boston Massachusetts USADepartment of Neurology Boston University School of Medicine Boston Massachusetts USACenter for Translational Cognitive Neuroscience VA Boston Healthcare System Boston Massachusetts USACenter for Translational Cognitive Neuroscience VA Boston Healthcare System Boston Massachusetts USADepartment of Radiology VA Boston Healthcare System Boston Massachusetts USACenter for Translational Cognitive Neuroscience VA Boston Healthcare System Boston Massachusetts USACenter for Translational Cognitive Neuroscience VA Boston Healthcare System Boston Massachusetts USAAbstract Introduction This study assessed the ordering of amyloid positron emission tomography (PET) scans in a Veterans Affairs (VA) memory disorders clinic as part of routine clinical care, with possible implications for the extent to which ordering may occur outside of the VA in the future if covered by insurance. Methods Clinical features predictive of ordering amyloid PET scans were retrospectively assessed; the percentage of patients who met appropriate use criteria were evaluated. Results Among 565 veterans, 34.9% of received an amyloid PET scan and 98.0% of these were consistent with appropriate use criteria. Patients with a PET were younger and more likely to have an initial diagnosis of Alzheimer's disease (AD). Of patients without an amyloid PET scan ordered, 64.4% would have met appropriate use criteria for amyloid PET. Discussion The majority of scans ordered were consistent with appropriate use criteria and more patients were eligible than received a scan. The current study's findings that approximately one‐third of patients in a memory disorders clinic received an amyloid PET scan has implications for memory disorders clinics inside and outside of the US Veterans Health Administration.https://doi.org/10.1002/trc2.12333Alzheimer's diseaseamyloid PETcognitive declinediagnosisbiomarker
spellingShingle Katherine W. Turk
Ana Vives‐Rodriguez
Kylie A. Schiloski
Anna Marin
Ryan Wang
Prabhjyot Singh
Gabor P. Hajos
Rachel Powsner
Renée DeCaro
Andrew E. Budson
Amyloid PET ordering practices in a memory disorders clinic
Alzheimer’s & Dementia: Translational Research & Clinical Interventions
Alzheimer's disease
amyloid PET
cognitive decline
diagnosis
biomarker
title Amyloid PET ordering practices in a memory disorders clinic
title_full Amyloid PET ordering practices in a memory disorders clinic
title_fullStr Amyloid PET ordering practices in a memory disorders clinic
title_full_unstemmed Amyloid PET ordering practices in a memory disorders clinic
title_short Amyloid PET ordering practices in a memory disorders clinic
title_sort amyloid pet ordering practices in a memory disorders clinic
topic Alzheimer's disease
amyloid PET
cognitive decline
diagnosis
biomarker
url https://doi.org/10.1002/trc2.12333
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