Differences in second trimester risk estimates for trisomy 21 between Maglumi X3/Preaccu and Immulite/Prisca systems

Maternal serum alpha-fetoprotein (AFP), human chorionic gonadotropin (HCG) or free β-HCG, and unconjugated estriol (uE3) concentrations are used to screen trisomy 21 in the second trimester. The performance of different analytical platforms has an impact on individual risk estimates. The aim of this...

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Main Authors: Üstündağ Yasemin, Huysal Kağan, Yeşil Meryem Rümeysa
Format: Article
Language:English
Published: De Gruyter 2024-12-01
Series:Türk Biyokimya Dergisi
Subjects:
Online Access:https://doi.org/10.1515/tjb-2023-0203
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author Üstündağ Yasemin
Huysal Kağan
Yeşil Meryem Rümeysa
author_facet Üstündağ Yasemin
Huysal Kağan
Yeşil Meryem Rümeysa
author_sort Üstündağ Yasemin
collection DOAJ
description Maternal serum alpha-fetoprotein (AFP), human chorionic gonadotropin (HCG) or free β-HCG, and unconjugated estriol (uE3) concentrations are used to screen trisomy 21 in the second trimester. The performance of different analytical platforms has an impact on individual risk estimates. The aim of this study is to compare the multiple of median (MoM) values and risk estimates generated by Maglumi X3 analyzer/Preaccu software with the Immulite 2000 XPi device/Prisca software.
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publisher De Gruyter
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series Türk Biyokimya Dergisi
spelling doaj-art-508bab222a7d4c45a8627d29b7779da32025-08-20T02:55:40ZengDe GruyterTürk Biyokimya Dergisi1303-829X2024-12-01501465110.1515/tjb-2023-0203Differences in second trimester risk estimates for trisomy 21 between Maglumi X3/Preaccu and Immulite/Prisca systemsÜstündağ Yasemin0Huysal Kağan1Yeşil Meryem Rümeysa2Department of Biochemistry, University of Health Sciences Bursa Yuksek Ihtisas Research and Training Hospital, Bursa, TürkiyeDepartment of Biochemistry, University of Health Sciences Bursa Yuksek Ihtisas Research and Training Hospital, Bursa, TürkiyeDepartment of Biochemistry, University of Health Sciences Bursa Yuksek Ihtisas Research and Training Hospital, Bursa, TürkiyeMaternal serum alpha-fetoprotein (AFP), human chorionic gonadotropin (HCG) or free β-HCG, and unconjugated estriol (uE3) concentrations are used to screen trisomy 21 in the second trimester. The performance of different analytical platforms has an impact on individual risk estimates. The aim of this study is to compare the multiple of median (MoM) values and risk estimates generated by Maglumi X3 analyzer/Preaccu software with the Immulite 2000 XPi device/Prisca software.https://doi.org/10.1515/tjb-2023-0203method comparisonmaglumi x3/preaccu systemsecond trimester down screeningrisk assessmentimmulite/prisca system
spellingShingle Üstündağ Yasemin
Huysal Kağan
Yeşil Meryem Rümeysa
Differences in second trimester risk estimates for trisomy 21 between Maglumi X3/Preaccu and Immulite/Prisca systems
Türk Biyokimya Dergisi
method comparison
maglumi x3/preaccu system
second trimester down screening
risk assessment
immulite/prisca system
title Differences in second trimester risk estimates for trisomy 21 between Maglumi X3/Preaccu and Immulite/Prisca systems
title_full Differences in second trimester risk estimates for trisomy 21 between Maglumi X3/Preaccu and Immulite/Prisca systems
title_fullStr Differences in second trimester risk estimates for trisomy 21 between Maglumi X3/Preaccu and Immulite/Prisca systems
title_full_unstemmed Differences in second trimester risk estimates for trisomy 21 between Maglumi X3/Preaccu and Immulite/Prisca systems
title_short Differences in second trimester risk estimates for trisomy 21 between Maglumi X3/Preaccu and Immulite/Prisca systems
title_sort differences in second trimester risk estimates for trisomy 21 between maglumi x3 preaccu and immulite prisca systems
topic method comparison
maglumi x3/preaccu system
second trimester down screening
risk assessment
immulite/prisca system
url https://doi.org/10.1515/tjb-2023-0203
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