miR-21 Regulates Immune Balance Mediated by Th17/Treg in Peripheral Blood of Septic Rats during the Early Phase through Apoptosis Pathway

Objective. To study the mechanism by which miR-21 regulates the differentiation and function of Th17/Treg cells in sepsis. Methods. A rat model with sepsis was made by cecal ligation and puncture (CLP). Then, some of the septic rats were transfected with miR-21 mimic or inhibitor by liposome. At 48 ...

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Bibliographic Details
Main Authors: Cheng Liu, Qi Zou
Format: Article
Language:English
Published: Wiley 2022-01-01
Series:Biochemistry Research International
Online Access:http://dx.doi.org/10.1155/2022/9948229
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