Optimized sensitivity of allele-specific PCR for prenatal typing of human platelet alloantigen single nucleotide polymorphisms

Optimized sensitivity of allele-specific PCR for prenatal typing of human platelet alloantigen single nucleotide polymorphisms

PCR using sequence-specific primers (PCR-SSP) is widely employed for the genotyping of single nucleotide polymorphisms (SNPs) in both routine diagnosis and medical research. The human platelet alloantigens (HPAs) represent SNPs in platelet-specific glycoproteins, and HPA-1, -2, -3, and -5 are the mo...

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Bibliographic Details
Main Authors: P. Bugert, A. Lese, J. Meckies, W. Zieger, H. Eichler, H. Klüter
Format: Article
Language:English
Published: Taylor & Francis Group 2003-07-01
Series:BioTechniques
Online Access:https://www.future-science.com/doi/10.2144/03351md05
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