Cell Sorting Using Diagonal Bottom Grooves in a Microchannel
Cell shape is related to cell function. For the purpose of cell sorting based on shape, a channel with diagonal grooves on the bottom was designed. A cell suspension was poured into a channel created by micromachining, and cell sorting according to shape was confirmed. Experimental results shows tha...
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| Format: | Article |
| Language: | English |
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International Institute of Informatics and Cybernetics
2024-04-01
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| Series: | Journal of Systemics, Cybernetics and Informatics |
| Subjects: | |
| Online Access: | http://www.iiisci.org/Journal/PDV/sci/pdfs/ZA167ZY24.pdf
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| _version_ | 1849714641001775104 |
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| author | Kota Yamamoto Shigehiro Hashimoto |
| author_facet | Kota Yamamoto Shigehiro Hashimoto |
| author_sort | Kota Yamamoto |
| collection | DOAJ |
| description | Cell shape is related to cell function. For the purpose of cell sorting based on shape, a channel with diagonal grooves on the bottom was designed. A cell suspension was poured into a channel created by micromachining, and cell sorting according to shape was confirmed. Experimental results shows that smaller and more elongated cells undergo a larger shift perpendicular to the mainstream direction during passing over the groove. Diagonal bottom grooves in a microchannel are effective for cell sorting. |
| format | Article |
| id | doaj-art-507afa47565e4456bc29d0f91c47d7b0 |
| institution | DOAJ |
| issn | 1690-4524 |
| language | English |
| publishDate | 2024-04-01 |
| publisher | International Institute of Informatics and Cybernetics |
| record_format | Article |
| series | Journal of Systemics, Cybernetics and Informatics |
| spelling | doaj-art-507afa47565e4456bc29d0f91c47d7b02025-08-20T03:13:39ZengInternational Institute of Informatics and CyberneticsJournal of Systemics, Cybernetics and Informatics1690-45242024-04-012224853Cell Sorting Using Diagonal Bottom Grooves in a MicrochannelKota YamamotoShigehiro HashimotoCell shape is related to cell function. For the purpose of cell sorting based on shape, a channel with diagonal grooves on the bottom was designed. A cell suspension was poured into a channel created by micromachining, and cell sorting according to shape was confirmed. Experimental results shows that smaller and more elongated cells undergo a larger shift perpendicular to the mainstream direction during passing over the groove. Diagonal bottom grooves in a microchannel are effective for cell sorting.http://www.iiisci.org/Journal/PDV/sci/pdfs/ZA167ZY24.pdf biomedical engineeringgrooves and microchannelcell sorting |
| spellingShingle | Kota Yamamoto Shigehiro Hashimoto Cell Sorting Using Diagonal Bottom Grooves in a Microchannel Journal of Systemics, Cybernetics and Informatics biomedical engineering grooves and microchannel cell sorting |
| title | Cell Sorting Using Diagonal Bottom Grooves in a Microchannel |
| title_full | Cell Sorting Using Diagonal Bottom Grooves in a Microchannel |
| title_fullStr | Cell Sorting Using Diagonal Bottom Grooves in a Microchannel |
| title_full_unstemmed | Cell Sorting Using Diagonal Bottom Grooves in a Microchannel |
| title_short | Cell Sorting Using Diagonal Bottom Grooves in a Microchannel |
| title_sort | cell sorting using diagonal bottom grooves in a microchannel |
| topic | biomedical engineering grooves and microchannel cell sorting |
| url | http://www.iiisci.org/Journal/PDV/sci/pdfs/ZA167ZY24.pdf
|
| work_keys_str_mv | AT kotayamamoto cellsortingusingdiagonalbottomgroovesinamicrochannel AT shigehirohashimoto cellsortingusingdiagonalbottomgroovesinamicrochannel |