Integration of Biological Synthesis & Chemical Catalysis: Bio-based Plasticizer trans-Aconitates

Plasticizers are essential to reduce processing difficulties and improve plastic properties. However, petroleum-based phthalate plasticizers, which are mostly used at present, urgently require alternatives due to their confirmed and serious health risks. In this study, the green mass production of t...

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Main Authors: Hongbin Hou, Xuenian Huang, Zhiqiang Du, Jian Guo, Min Wang, Guangqiang Xu, Ce Geng, Yunpeng Zhang, Qinggang Wang, Xuefeng Lu
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2023-09-01
Series:Green Carbon
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Online Access:http://www.sciencedirect.com/science/article/pii/S2950155523000058
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author Hongbin Hou
Xuenian Huang
Zhiqiang Du
Jian Guo
Min Wang
Guangqiang Xu
Ce Geng
Yunpeng Zhang
Qinggang Wang
Xuefeng Lu
author_facet Hongbin Hou
Xuenian Huang
Zhiqiang Du
Jian Guo
Min Wang
Guangqiang Xu
Ce Geng
Yunpeng Zhang
Qinggang Wang
Xuefeng Lu
author_sort Hongbin Hou
collection DOAJ
description Plasticizers are essential to reduce processing difficulties and improve plastic properties. However, petroleum-based phthalate plasticizers, which are mostly used at present, urgently require alternatives due to their confirmed and serious health risks. In this study, the green mass production of trans-aconitic acid was achieved via synthetic biotechnology and microbial fermentation, which was further expanded to multiple application scenarios using chemical esterification, resulting in trans-aconitate plasticizers that are biosafe and environmentally friendly and have high plasticizing efficiency and long-term stability. Different plasticizers with various core structures and alkyl chains were studied to determine their properties as polyvinyl chloride (PVC) plasticizers, and tributyl trans-aconitate displayed the best comprehensive performance with up to 1.24 plasticizing efficiency. The possible PVC plasticization mechanism with synergistic solvent, support, and shielding effects was discussed and summarized. Tributyl trans-aconitate has significant potential to replace traditional PVC plasticizers in general merchandise, food packaging, medicinal materials, and other products, further promoting the development of the high-quality plastic industry with greener technology and safer applications.
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id doaj-art-50755724d09e456f9dfcd7f00964761f
institution OA Journals
issn 2950-1555
language English
publishDate 2023-09-01
publisher KeAi Communications Co., Ltd.
record_format Article
series Green Carbon
spelling doaj-art-50755724d09e456f9dfcd7f00964761f2025-08-20T01:49:31ZengKeAi Communications Co., Ltd.Green Carbon2950-15552023-09-0111203210.1016/j.greenca.2023.08.001Integration of Biological Synthesis & Chemical Catalysis: Bio-based Plasticizer trans-AconitatesHongbin Hou0Xuenian Huang1Zhiqiang Du2Jian Guo3Min Wang4Guangqiang Xu5Ce Geng6Yunpeng Zhang7Qinggang Wang8Xuefeng Lu9Key Laboratory of Biofuels, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, Qingdao 266101, China; Shandong Energy Institute, Qingdao 266101, China; Qingdao New Energy Shandong Laboratory, Qingdao 266101, ChinaShandong Provincial Key Laboratory of Synthetic Biology, Qingdao 266101, China; Shandong Energy Institute, Qingdao 266101, China; Qingdao New Energy Shandong Laboratory, Qingdao 266101, China; University of Chinese Academy of Sciences, Beijing 100049, ChinaShandong Provincial Key Laboratory of Synthetic Biology, Qingdao 266101, China; Shandong Energy Institute, Qingdao 266101, China; Qingdao New Energy Shandong Laboratory, Qingdao 266101, ChinaKey Laboratory of Biofuels, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, Qingdao 266101, China; Shandong Energy Institute, Qingdao 266101, China; Qingdao New Energy Shandong Laboratory, Qingdao 266101, ChinaShandong Provincial Key Laboratory of Synthetic Biology, Qingdao 266101, China; Shandong Energy Institute, Qingdao 266101, China; Qingdao New Energy Shandong Laboratory, Qingdao 266101, ChinaKey Laboratory of Biofuels, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, Qingdao 266101, China; Shandong Energy Institute, Qingdao 266101, China; Qingdao New Energy Shandong Laboratory, Qingdao 266101, ChinaShandong Provincial Key Laboratory of Synthetic Biology, Qingdao 266101, China; Shandong Energy Institute, Qingdao 266101, China; Qingdao New Energy Shandong Laboratory, Qingdao 266101, ChinaShandong Provincial Key Laboratory of Synthetic Biology, Qingdao 266101, China; Shandong Energy Institute, Qingdao 266101, China; Qingdao New Energy Shandong Laboratory, Qingdao 266101, ChinaKey Laboratory of Biofuels, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, Qingdao 266101, China; Shandong Energy Institute, Qingdao 266101, China; Qingdao New Energy Shandong Laboratory, Qingdao 266101, China; University of Chinese Academy of Sciences, Beijing 100049, China; Corresponding authors.Shandong Provincial Key Laboratory of Synthetic Biology, Qingdao 266101, China; Key Laboratory of Biofuels, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, Qingdao 266101, China; Shandong Energy Institute, Qingdao 266101, China; Qingdao New Energy Shandong Laboratory, Qingdao 266101, China; University of Chinese Academy of Sciences, Beijing 100049, China; Marine Biology and Biotechnology Laboratory, Qingdao National Laboratory for Marine Science and Technology, Qingdao 266237, China; Corresponding authors.Plasticizers are essential to reduce processing difficulties and improve plastic properties. However, petroleum-based phthalate plasticizers, which are mostly used at present, urgently require alternatives due to their confirmed and serious health risks. In this study, the green mass production of trans-aconitic acid was achieved via synthetic biotechnology and microbial fermentation, which was further expanded to multiple application scenarios using chemical esterification, resulting in trans-aconitate plasticizers that are biosafe and environmentally friendly and have high plasticizing efficiency and long-term stability. Different plasticizers with various core structures and alkyl chains were studied to determine their properties as polyvinyl chloride (PVC) plasticizers, and tributyl trans-aconitate displayed the best comprehensive performance with up to 1.24 plasticizing efficiency. The possible PVC plasticization mechanism with synergistic solvent, support, and shielding effects was discussed and summarized. Tributyl trans-aconitate has significant potential to replace traditional PVC plasticizers in general merchandise, food packaging, medicinal materials, and other products, further promoting the development of the high-quality plastic industry with greener technology and safer applications.http://www.sciencedirect.com/science/article/pii/S2950155523000058Bio-based plasticizerMicrobial productionTrans-Aconitic acidTributyl trans-aconitateSynthetic plastics
spellingShingle Hongbin Hou
Xuenian Huang
Zhiqiang Du
Jian Guo
Min Wang
Guangqiang Xu
Ce Geng
Yunpeng Zhang
Qinggang Wang
Xuefeng Lu
Integration of Biological Synthesis & Chemical Catalysis: Bio-based Plasticizer trans-Aconitates
Green Carbon
Bio-based plasticizer
Microbial production
Trans-Aconitic acid
Tributyl trans-aconitate
Synthetic plastics
title Integration of Biological Synthesis & Chemical Catalysis: Bio-based Plasticizer trans-Aconitates
title_full Integration of Biological Synthesis & Chemical Catalysis: Bio-based Plasticizer trans-Aconitates
title_fullStr Integration of Biological Synthesis & Chemical Catalysis: Bio-based Plasticizer trans-Aconitates
title_full_unstemmed Integration of Biological Synthesis & Chemical Catalysis: Bio-based Plasticizer trans-Aconitates
title_short Integration of Biological Synthesis & Chemical Catalysis: Bio-based Plasticizer trans-Aconitates
title_sort integration of biological synthesis amp chemical catalysis bio based plasticizer trans aconitates
topic Bio-based plasticizer
Microbial production
Trans-Aconitic acid
Tributyl trans-aconitate
Synthetic plastics
url http://www.sciencedirect.com/science/article/pii/S2950155523000058
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