Association between body composition components and electrocardiogram parameters: results from the Fasa Adults Cohort Study (FACS)
Abstract Objective Cardiovascular diseases as the leading cause of death and disability are increasing worldwide. The present study aimed to investigate the association between total body water, total fat percent, and trunk fat percent with electrocardiogram (ECG) parameters in the Persian Fasa Adul...
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BMC
2025-04-01
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| Series: | European Journal of Medical Research |
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| Online Access: | https://doi.org/10.1186/s40001-025-02569-5 |
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| author | Mehdi Sharafi Sima Afrashteh Mojtaba Farjam Omid Keshavarzian Mohammad Amin Annabi Toolgilani Hanie Aboughadare Sanaz Dastmanedh Maryam Talebi Moghaddam |
| author_facet | Mehdi Sharafi Sima Afrashteh Mojtaba Farjam Omid Keshavarzian Mohammad Amin Annabi Toolgilani Hanie Aboughadare Sanaz Dastmanedh Maryam Talebi Moghaddam |
| author_sort | Mehdi Sharafi |
| collection | DOAJ |
| description | Abstract Objective Cardiovascular diseases as the leading cause of death and disability are increasing worldwide. The present study aimed to investigate the association between total body water, total fat percent, and trunk fat percent with electrocardiogram (ECG) parameters in the Persian Fasa Adult Cohort Study (FACS). Methods This cross-sectional study was performed on the baseline information obtained from 3217 35–70-year-old participants of the FACS, southern Iran. Various ECG and body composition parameters were obtained from the FACS baseline database. Independent t-test, Chi-square test and linear regression were used for data analysis. Results Total body water (TBW) was positively associated with QRS length in men and women, and with PD and PR interval in women, exclusively. Additionally, in participants without chronic diseases (healthy group), TBW was shown to be positively associated with QRS length and PD; however, it was associated with QRS length and S wave in V3 lead (SV3) among those with type two diabetes, hypertension or ischemic heart disease (defined as unhealthy group). Total body fat percent (TBFP) was linearly associated with SV3 in unhealthy group. None of the studied ECG parameters was associated with TBFP in men, women and healthy group. Moreover, trunk fat percent was shown to be positive associated with R wave in aVL lead in women and unhealthy groups. Conclusion Body fat percentage and fat distribution may affect ECG parameters, and subsequently associated with cardiovascular diseases, such as arrhythmias. Thus, these indicators may carry the potential for screening high-risk individuals. |
| format | Article |
| id | doaj-art-50625fffb7a64733bc8c31c05bd1a15f |
| institution | OA Journals |
| issn | 2047-783X |
| language | English |
| publishDate | 2025-04-01 |
| publisher | BMC |
| record_format | Article |
| series | European Journal of Medical Research |
| spelling | doaj-art-50625fffb7a64733bc8c31c05bd1a15f2025-08-20T02:24:29ZengBMCEuropean Journal of Medical Research2047-783X2025-04-0130111010.1186/s40001-025-02569-5Association between body composition components and electrocardiogram parameters: results from the Fasa Adults Cohort Study (FACS)Mehdi Sharafi0Sima Afrashteh1Mojtaba Farjam2Omid Keshavarzian3Mohammad Amin Annabi Toolgilani4Hanie Aboughadare5Sanaz Dastmanedh6Maryam Talebi Moghaddam7School of Nursing, Gerash University of Medical SciencesClinical Research Development Center, The Persian Gulf Martyrs Hospital, Bushehr University of Medical SciencesNoncommunicable Diseases Research Center, Fasa University of Medical SciencesTransplant Research Center, Shiraz University of Medical SciencesSchool of Medicine, Shiraz University of Medical SciencesStudents Research Committee, Shiraz University of Medical SciencesNoncommunicable Diseases Research Center, Fasa University of Medical SciencesNoncommunicable Diseases Research Center, Fasa University of Medical SciencesAbstract Objective Cardiovascular diseases as the leading cause of death and disability are increasing worldwide. The present study aimed to investigate the association between total body water, total fat percent, and trunk fat percent with electrocardiogram (ECG) parameters in the Persian Fasa Adult Cohort Study (FACS). Methods This cross-sectional study was performed on the baseline information obtained from 3217 35–70-year-old participants of the FACS, southern Iran. Various ECG and body composition parameters were obtained from the FACS baseline database. Independent t-test, Chi-square test and linear regression were used for data analysis. Results Total body water (TBW) was positively associated with QRS length in men and women, and with PD and PR interval in women, exclusively. Additionally, in participants without chronic diseases (healthy group), TBW was shown to be positively associated with QRS length and PD; however, it was associated with QRS length and S wave in V3 lead (SV3) among those with type two diabetes, hypertension or ischemic heart disease (defined as unhealthy group). Total body fat percent (TBFP) was linearly associated with SV3 in unhealthy group. None of the studied ECG parameters was associated with TBFP in men, women and healthy group. Moreover, trunk fat percent was shown to be positive associated with R wave in aVL lead in women and unhealthy groups. Conclusion Body fat percentage and fat distribution may affect ECG parameters, and subsequently associated with cardiovascular diseases, such as arrhythmias. Thus, these indicators may carry the potential for screening high-risk individuals.https://doi.org/10.1186/s40001-025-02569-5ElectrocardiographyBody compositionBody waterTotal fat percentTrunk fat percent |
| spellingShingle | Mehdi Sharafi Sima Afrashteh Mojtaba Farjam Omid Keshavarzian Mohammad Amin Annabi Toolgilani Hanie Aboughadare Sanaz Dastmanedh Maryam Talebi Moghaddam Association between body composition components and electrocardiogram parameters: results from the Fasa Adults Cohort Study (FACS) European Journal of Medical Research Electrocardiography Body composition Body water Total fat percent Trunk fat percent |
| title | Association between body composition components and electrocardiogram parameters: results from the Fasa Adults Cohort Study (FACS) |
| title_full | Association between body composition components and electrocardiogram parameters: results from the Fasa Adults Cohort Study (FACS) |
| title_fullStr | Association between body composition components and electrocardiogram parameters: results from the Fasa Adults Cohort Study (FACS) |
| title_full_unstemmed | Association between body composition components and electrocardiogram parameters: results from the Fasa Adults Cohort Study (FACS) |
| title_short | Association between body composition components and electrocardiogram parameters: results from the Fasa Adults Cohort Study (FACS) |
| title_sort | association between body composition components and electrocardiogram parameters results from the fasa adults cohort study facs |
| topic | Electrocardiography Body composition Body water Total fat percent Trunk fat percent |
| url | https://doi.org/10.1186/s40001-025-02569-5 |
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