Targeting the mTOR Signaling Pathway Through miR‐100 and miR‐101 in De Novo Acute Myeloid Leukemia: Implications for Therapeutic Intervention

Targeting the mTOR Signaling Pathway Through miR‐100 and miR‐101 in De Novo Acute Myeloid Leukemia: Implications for Therapeutic Intervention

ABSTRACT Background Microribonucleic acid (MicroRNAs/miRNAs) play a significant role in cancer progression by changing cellular functions through the modulation of protein expressions. The potential of different miRNAs to alter the expression of the mammalian target of rapamycin (mTOR)/protein kinas...

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Bibliographic Details
Main Authors: Maryam Kargar, Mehdi Allahbakhshian Farsani, Javad Garavand, Mahnaz Gorji, Mohammad Rafiee, Seyed Sobhan Bahreiny, Mohammad Hossein Mohammadi
Format: Article
Language:English
Published: Wiley 2025-08-01
Series:Cancer Reports
Subjects:
acute myeloid leukemia
microRNA‐100
microRNA‐101
mTOR/AKT/PI3K pathway
Online Access:https://doi.org/10.1002/cnr2.70264
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