In Vitro Antimicrobial Screening of Alkaloid Fractions from Strychnos potatorum

Alkaloid fractions isolated from Strychnos potatorum L.f. (Loganiaceae) seed were tested for their antimicrobial properties against some pathogenic gram positive, gram negative and acid-fast bacteria and fungi. These fractions have shown considerable antimicrobial activity against both bacteria and...

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Main Authors: P. B. Mallikharjuna, Y. N. Seetharam
Format: Article
Language:English
Published: Wiley 2009-01-01
Series:E-Journal of Chemistry
Online Access:http://dx.doi.org/10.1155/2009/535643
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author P. B. Mallikharjuna
Y. N. Seetharam
author_facet P. B. Mallikharjuna
Y. N. Seetharam
author_sort P. B. Mallikharjuna
collection DOAJ
description Alkaloid fractions isolated from Strychnos potatorum L.f. (Loganiaceae) seed were tested for their antimicrobial properties against some pathogenic gram positive, gram negative and acid-fast bacteria and fungi. These fractions have shown considerable antimicrobial activity against both bacteria and fungi at the tested concentrations (100 & 200 μg/mL). Further, the growth of Proteus vulgaris, taphylococcus aureus, Salmonella typhimurium, Vibrio cholerae, Mycobacterium tuberculosis, Aspergillus niger and Candida albicans were significantly inhibited. These findings have confirmed the use of this plant in treating of several microbial infections both in traditional and folk medicine in India.
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institution Kabale University
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spelling doaj-art-5051d4ff649a41db9875eb89da76ceb82025-08-20T03:36:15ZengWileyE-Journal of Chemistry0973-49452090-98102009-01-01641200120410.1155/2009/535643In Vitro Antimicrobial Screening of Alkaloid Fractions from Strychnos potatorumP. B. Mallikharjuna0Y. N. Seetharam1Laboratory of Biosystematics and Medicinal Plants, Department of PG Studies & Research in Botany, Gulbarga University, Gulbarga-585 106, IndiaLaboratory of Biosystematics and Medicinal Plants, Department of PG Studies & Research in Botany, Gulbarga University, Gulbarga-585 106, IndiaAlkaloid fractions isolated from Strychnos potatorum L.f. (Loganiaceae) seed were tested for their antimicrobial properties against some pathogenic gram positive, gram negative and acid-fast bacteria and fungi. These fractions have shown considerable antimicrobial activity against both bacteria and fungi at the tested concentrations (100 & 200 μg/mL). Further, the growth of Proteus vulgaris, taphylococcus aureus, Salmonella typhimurium, Vibrio cholerae, Mycobacterium tuberculosis, Aspergillus niger and Candida albicans were significantly inhibited. These findings have confirmed the use of this plant in treating of several microbial infections both in traditional and folk medicine in India.http://dx.doi.org/10.1155/2009/535643
spellingShingle P. B. Mallikharjuna
Y. N. Seetharam
In Vitro Antimicrobial Screening of Alkaloid Fractions from Strychnos potatorum
E-Journal of Chemistry
title In Vitro Antimicrobial Screening of Alkaloid Fractions from Strychnos potatorum
title_full In Vitro Antimicrobial Screening of Alkaloid Fractions from Strychnos potatorum
title_fullStr In Vitro Antimicrobial Screening of Alkaloid Fractions from Strychnos potatorum
title_full_unstemmed In Vitro Antimicrobial Screening of Alkaloid Fractions from Strychnos potatorum
title_short In Vitro Antimicrobial Screening of Alkaloid Fractions from Strychnos potatorum
title_sort in vitro antimicrobial screening of alkaloid fractions from strychnos potatorum
url http://dx.doi.org/10.1155/2009/535643
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